Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31378785 | 0.85 | MAP2K3 (0.51) | AXLMAP2K3 | |
| SCHEMBL15971706 | 0.84 | BTK (0.37) | AXL | |
| SCHEMBL17837770 | 0.81 | GPR119 (0.51) | AXL | |
| SCHEMBL17861720 | 0.81 | PIM3 (0.48) | AXLMAP2K3 | |
| SCHEMBL25721094 | 0.80 | MAP2K3 (0.46) | AXLMAP2K3 | |
| SCHEMBL30308868 | 0.80 | MAP2K3 (0.46) | AXLMAP2K3 | |
| SCHEMBL22119683 | 0.78 | TRPC6 (0.40) | — | |
| SCHEMBL17837643 | 0.78 | MAP2K3 (0.45) | AXLMAP2K3 | |
| SCHEMBL17837960 | 0.78 | AXL (0.51) | AXL | |
| Hydrochloric Acid SCHEMBL17837951 | 0.77 | MAP2K3 (0.44) | AXLMAP2K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233829-A1 | PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS | Pfizer Inc (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097918-A1 | PYRIMIDINE AND TRIAZINE DERIVATIVES AND THEIR USE AS AXL INHIBITORS | PFIZER INC. (US) | 2016-06-23 | — | — | WO | disclosed |