Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914803 | 0.73 | ALDH1A1 (0.56) | ALDH1A1CYP2C19MAPTCDK1CDK4 | |
| SCHEMBL8553879 | 0.72 | ALDH1A1 (0.55) | ALDH1A1CYP2C19MAPTCDK1CDK4 | |
| SCHEMBL4570273 | 0.70 | ALDH1A1 (0.54) | ALDH1A1CYP2C19MAPTCDK1CDK4 | |
| SCHEMBL29952359 | 0.69 | PNP (0.34) | MAPTCDK1CDK4CDK2PNP | |
| SCHEMBL9513541 | 0.68 | GAA (0.44) | ALDH1A1CYP2C19MAPTPNP | |
| SCHEMBL460884 | 0.68 | PNP (0.39) | ALDH1A1MAPTCDK1CDK4CDK2 | |
| SCHEMBL2953009 | 0.67 | KMT2A (0.41) | — | |
| SCHEMBL7167381 | 0.64 | PNP (0.43) | MAPTCDK1CDK4CDK2PNP | |
| SCHEMBL3180702 | 0.64 | PNP (0.37) | MAPTCDK1CDK4CDK2PNP | |
| SCHEMBL14217450 | 0.64 | TYMP (0.43) | ALDH1A1MAPTCDK1CDK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113088557-B | Fluorescent chemical sensor for simultaneously detecting multiple DNA glycosylases and detection method and application thereof | 山东师范大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-113088557-A | Fluorescent chemical sensor for simultaneously detecting multiple DNA glycosylases and detection method and application thereof | 山东师范大学 | 2021-07-09 | — | — | CN | disclosed |
| US-20200277649-A1 | BROAD SPECTRUM DETECTION OF DNA DAMAGE BY REPAIR ASSISTED DAMAGE DETECTION (RADD) | RAMOT AT TEL AVIV UNIVERSITY, LTD (IL) | 2020-09-03 | — | — | US | disclosed |
| WO-2019051043-A1 | BROAD SPECTRUM DETECTION OF DNA DAMAGE BY REPAIR ASSISTED DAMAGE DETECTION (RADD) | UNIVERSITY OF SOUTH ALABAMA (US) | 2019-03-14 | — | — | WO | disclosed |
| US-20180051316-A1 | DETECTION OF NUCLEIC ACID POLYMERASE CONFORMATIONAL CHANGES USING A NANOTUBE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-02-22 | — | — | US | disclosed |
| EP-3234178-A1 | DETECTION OF NUCLEIC ACID POLYMERASE CONFORMATIONAL CHANGES USING A NANOTUBE | The Regents of The University of California (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100635-A1 | DETECTION OF NUCLEIC ACID POLYMERASE CONFORMATIONAL CHANGES USING A NANOTUBE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016100637-A1 | DETECTION OF NUCLEIC ACID POLYMERASE CONFORMATIONAL CHANGES USING A NANOTUBE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-06-23 | — | — | WO | disclosed |