SCHEMBL17844649

SCHEMBL17844649

C=CC(=O)OC(CC)c1ccccc1.[NaH]

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.41
HCAR2 Q8TDS4 1/20 0.41
CYP2C19 P33261 1/20 0.40
LMNA P02545 5/20 0.39
KLK7 P49862 1/20 0.38
THRA P10827 1/20 0.38
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.37
PABPC1 P11940 1/20 0.37
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
MDM4 O15151 1/20 0.37
MAPT P10636 1/20 0.37
MDM2 Q00987 1/20 0.37
HSD17B10 Q99714 1/20 0.36
ALKBH1 Q13686 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1371364 0.98 THRB (0.41) THRBHCAR2CYP2C19LMNAKLK7
Acetic Acid SCHEMBL28013205 0.95 THRB (0.40) THRBHCAR2CYP2C19LMNAKLK7
Propionic Acid SCHEMBL28013214 0.94 THRB (0.39) THRBHCAR2CYP2C19LMNAKLK7
Sulfuric Acid SCHEMBL28055050 0.92 THRB (0.38) THRBHCAR2CYP2C19LMNAKLK7
SCHEMBL28013206 0.92 HCAR2 (0.41) THRBHCAR2CYP2C19LMNAKLK7
Methacrylic Acid SCHEMBL27994748 0.91 KLK7 (0.37) THRBHCAR2CYP2C19LMNAKLK7
3-Methylbutanoic Acid SCHEMBL28013211 0.89 FFAR1 (0.41) THRBHCAR2CYP2C19LMNAKMT2A
SCHEMBL3171202 0.86 THRB (0.40) THRBHCAR2CYP2C19THRAPOLB
SCHEMBL12391681 0.85 THRB (0.38) THRBTHRAMAPT
SCHEMBL17439438 0.85 HCAR2 (0.40) THRBHCAR2CYP2C19LMNAKLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3234023-A1 EFFECT PIGMENTS HAVING HIGH TRANSPARENCY, HIGH CHROMA AND HIGH BRILLIANCY, METHOD FOR THE PRODUCTION AND USE THEREOF Eckart GmbH (DE) 2017-10-25 EP disclosed
WO-2016097416-A1 EFFECT PIGMENTS HAVING HIGH TRANSPARENCY, HIGH CHROMA AND HIGH BRILLIANCY, METHOD FOR THE PRODUCTION AND USE THEREOF ECKART GMBH (DE) 2016-06-23 WO disclosed