SCHEMBL17844663

SCHEMBL17844663

O=C(O)c1ccc(C2CC2)[nH]c1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.47
KDM5A P29375 2/20 0.45
KDM5B Q9UGL1 2/20 0.45
ALDH1A1 P00352 3/20 0.41
GAA P10253 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
NAPRT Q6XQN6 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4A O75164 3/20 0.38
KDM3B Q7LBC6 2/20 0.38
KDM6B O15054 2/20 0.38
KDM4D Q6B0I6 2/20 0.38
HIF1AN Q9NWT6 2/20 0.38
KDM2A Q9Y2K7 2/20 0.38
KDM4C Q9H3R0 1/20 0.38
DAO P14920 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25148777 0.92 KDM4E (0.41) KDM4EKDM5AKDM5BALDH1A1GAA
SCHEMBL11833334 0.91 KDM5A (0.47) KDM4EKDM5AKDM5BALDH1A1GAA
SCHEMBL25148750 0.88 KDM4E (0.39) KDM4EKDM5AKDM5BALDH1A1GAA
SCHEMBL25148778 0.88 KDM4E (0.39) KDM4EKDM5AKDM5BALDH1A1GAA
SCHEMBL25148783 0.88 KDM4E (0.39) KDM4EKDM5AKDM5BALDH1A1GAA
SCHEMBL25148754 0.86 KDM4E (0.40) KDM4EKDM5AKDM5BALDH1A1GAA
SCHEMBL16794594 0.80 KDM5A (0.36) KDM4EKDM5AKDM5BALDH1A1GAA
SCHEMBL25149577 0.77 PARP1 (0.35) ALDH1A1GAASMN1; SMN2DAO
SCHEMBL30430358 0.75 HCAR2 (0.43) KDM4EKDM5AKDM5BSMN1; SMN2HCAR2
SCHEMBL17844664 0.74 DAO (0.34) KDM4EKDM5AKDM5BALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016096942-A1 USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-23 WO disclosed