Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764913 | 0.95 | ALDH1A1 (0.33) | PDK1ALDH1A1POLBHTTNPSR1 | |
| SCHEMBL6906654 | 0.89 | ALDH1A1 (0.33) | ALDH1A1HTT | |
| SCHEMBL9160306 | 0.89 | ALDH1A1 (0.33) | ALDH1A1HTT | |
| SCHEMBL30028753 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL8496317 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9349040 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL31190500 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL9144919 | 0.86 | TSHR (0.33) | MEN1KMT2A | |
| SCHEMBL2430458 | 0.86 | TSHR (0.33) | MEN1KMT2A | |
| SCHEMBL8075279 | 0.84 | MAPT (0.34) | PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095088-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-23 | — | — | WO | disclosed |