SCHEMBL14764913

SCHEMBL14764913

CCCC(O)OC1CCCO1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
HTT P42858 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 2/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDK1 Q15118 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17844871 0.95 MEN1 (0.31) ALDH1A1POLBHTTNPSR1PDK1
SCHEMBL9160306 0.83 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL6906654 0.83 ALDH1A1 (0.33) ALDH1A1HTT
SCHEMBL30028753 0.82 ALDH1A1 (0.36) ALDH1A1HTT
SCHEMBL8496317 0.82 ALDH1A1 (0.36) ALDH1A1HTT
SCHEMBL9349040 0.82 ALDH1A1 (0.36) ALDH1A1HTT
SCHEMBL31190500 0.82 ALDH1A1 (0.36) ALDH1A1HTT
SCHEMBL26108558 0.81 ALDH1A1 (0.30) ALDH1A1HPGDMAPTTSHRSMN1; SMN2
SCHEMBL9144919 0.80 TSHR (0.33) TSHR
SCHEMBL2430458 0.80 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103044365-B Production method of tetrahydrofuran CHINA PETROLEUM & CHEMICAL 2015-06-17 CN claimed
US-12479782-B2 Catalysts, preparation method thereof, and selective hydrogenation processes W.R. GRACE & CO. CONN. (US) 2025-11-25 US disclosed
US-20250162967-A1 PROCESS FOR PRODUCING A REFINED 1,4-BUTANEDIOL STREAM JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) 2025-05-22 US disclosed
CN-119657155-A Catalyst, process for its preparation and process for selective hydrogenation 格雷斯公司 2025-03-21 CN disclosed
CN-115160545-B Process for producing 1, 4-butanediol from renewable resources and polyesters obtained therefrom 诺瓦蒙特股份公司 2024-05-17 CN disclosed
WO-2023170409-A1 PROCESS FOR PRODUCING A REFINED 1,4-BUTANEDIOL STREAM JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) 2023-09-14 WO disclosed
US-20230051744-A1 CATALYSTS, PREPARATION METHOD THEREOF, AND SELECTIVE HYDROGENATION PROCESSES W. R. GRACE & CO.-CONN. (US) 2023-02-16 US disclosed
US-11498891-B2 Catalysts, preparation method thereof, and selective hydrogenation processes W.R. GRACE & CO.-CONN (US) 2022-11-15 US disclosed
CN-115160545-A Process for producing 1,4-butanediol from renewable resources and polyesters obtained therefrom 诺瓦蒙特股份公司 2022-10-11 CN disclosed
CN-111601648-B Process for the production of 1, 4-butanediol from renewable resources and polyester obtained therefrom 诺瓦蒙特股份公司 2022-08-02 CN disclosed
CN-103044198-B A kind of method of BDO purifying co-producing tetrahydrofuran SINOPEC CORP. (CN) 2015-10-21 CN disclosed
CN-103044198-B A kind of method of BDO purifying co-producing tetrahydrofuran SINOPEC CORP. (CN) 2015-10-21 CN disclosed
CN-103044197-B Technological method for purifying1,4-butanediol and co-producing gamma-butyrolactone CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed
CN-103044365-B Production method of tetrahydrofuran CHINA PETROLEUM & CHEMICAL 2015-06-17 CN disclosed
US-9040756-B2 Process for producing 1,4-butanediol by hydrogenating dialkyl maleate in mixed liquid/vapor phase CONSER SPA (IT) 2015-05-26 US disclosed
WO-2014170759-A2 PROCESS OF PRODUCING 1,4-BUTANEDIOL TORAY INDUSTRIES, INC. (JP) 2014-10-23 WO disclosed
US-20140316146-A1 PROCESS FOR PRODUCING 1,4- BUTANEDIOL BY HYDROGENATING DIALKYL MALEATE IN MIXED LIQUID/VAPOR PHASE CONSER SPA (IT) 2014-10-23 US disclosed
EP-2782893-A1 PROCESS FOR PRODUCING 1,4- BUTANEDIOL BY HYDROGENATING DIALKYL MALEATE IN MIXED LIQUID/VAPOR PHASE Conser S.P.A. (IT) 2014-10-01 EP disclosed
WO-2013076747-A1 PROCESS FOR PRODUCING 1,4- BUTANEDIOL BY HYDROGENATING DIALKYL MALEATE IN MIXED LIQUID/VAPOR PHASE CONSER SPA (IT) 2013-05-30 WO disclosed
WO-2013034881-A1 PROCESS FOR PURIFYING A STREAM COMPRISING 1,4- BUTANEDIOL DAVY PROCESS TECHNOLOGY LIMITED (GB) 2013-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250162967-A1 PROCESS FOR PRODUCING A REFINED 1,4-BUTANEDIOL STREAM HSD17B7, ADH1C, SORD ALDH1A1 219/4885POLB 122/4885HTT 1044/4885
US-20140316146-A1 PROCESS FOR PRODUCING 1,4- BUTANEDIOL BY HYDROGENATING DIALKYL MALEATE IN MIXED LIQUID/VAPOR PHASE SDHA, BCKDK, HPD ALDH1A1 373/4885POLB 720/4885HTT 840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.