SCHEMBL1784498

SCHEMBL1784498

CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSL P07711 4/20 0.62
GAA P10253 1/20 0.59
RAB9A P51151 1/20 0.59
ACE P12821 1/20 0.57
TSHR P16473 1/20 0.55
LNPEP Q9UIQ6 1/20 0.55
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
GLA P06280 1/20 0.52
MDM4 O15151 1/20 0.52
MDM2 Q00987 1/20 0.52
BACE1 P56817 1/20 0.52
GRIA1 P42261 1/20 0.52
CTSS P25774 1/20 0.51
CTSK P43235 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3935180 1.00 CTSL (0.62) CTSLGAARAB9AACETSHR
SCHEMBL30064651 1.00 CTSL (0.62) CTSLGAARAB9AACETSHR
SCHEMBL1796825 1.00 CTSL (0.62) CTSLGAARAB9AACETSHR
SCHEMBL6674337 0.99 CTSL (0.61) CTSLGAARAB9AACETSHR
SCHEMBL3927110 0.95 CTSL (0.58) CTSLGAARAB9AACETSHR
SCHEMBL28790851 0.92 CTSL (0.71) CTSLGAARAB9AACEALDH1A1
SCHEMBL3927028 0.92 CTSL (0.71) CTSLGAARAB9AACEALDH1A1
SCHEMBL27761117 0.91 CTSL (0.62) CTSLGAARAB9AACEALDH1A1
SCHEMBL3928165 0.89 LNPEP (0.67) CTSLGAARAB9AACETSHR
SCHEMBL3928164 0.89 LNPEP (0.67) CTSLGAARAB9AACETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025202803-A1 A PROCESS FOR PREPARING LACTOBACILLUS-BASED RECOMBINANT VACCINE CANDIDATE AGAINST MULTIPLE SALMONELLA SEROVAR IN POULTRY AHMAD SYED MUDASIR (IN) 2025-10-02 WO claimed
CN-119868526-B Nanometer vaccine based on helicobacter pylori outer membrane vesicle, and preparation method and application thereof 广东工业大学 2025-06-03 CN claimed
CN-119868526-A Nanometer vaccine based on helicobacter pylori outer membrane vesicle, and preparation method and application thereof 广东工业大学 2025-04-25 CN claimed
CN-119701900-A Hydrophilic core-shell silica gel stationary phase for separating saccharide components, and preparation method and application thereof 山西大学 2025-03-28 CN claimed
US-20240358647-A1 Protease Inhibitor-Containing Compositions, Compositions Comprising Same, and Methods for Producing and Using Same ORAMED LTD. (IL) 2024-10-31 US claimed
US-20240216325-A1 NUCLEAR FACTOR KAPPA B PATHWAY INHIBITION TO ARREST CALCIFIC AORTIC STENOSIS CORNELL UNIVERSITY 2024-07-04 US claimed
CN-118079988-A Ternary composite photocatalytic material and preparation method and application thereof 华南理工大学 2024-05-28 CN claimed
CN-116706230-B High-voltage electrolyte for lithium battery 浙江大学 2024-02-02 CN claimed
CN-117224707-A Anti-nitrification nano-material, and preparation method and application thereof 复旦大学附属眼耳鼻喉科医院 2023-12-15 CN claimed
CN-116706230-A High-voltage electrolyte for lithium battery 浙江大学 2023-09-05 CN claimed
CN-109187806-A A kind of general quality control method of liquid chromatograph mass spectrography metabolism group detection 嘉兴迈维代谢生物科技有限公司 2019-01-11 CN claimed
US-20040229303-A1 Novel thermostable proteolytic enzymes and uses thereof in peptide and protein synthesis THE UNIVERSITY OF FLORIDA (US) 2004-11-18 US claimed
US-6743618-B2 AN ISOLATED SERINE PROTEASE IS ENCODED BY A POLYNUCLEOTIDE SEQUENCE OR A HYBRIDS; ACTIVE AT TEMPERATURES OF ABOUT 80 DEGREES C. OR HIGHER UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2004-06-01 US claimed
US-6420424-B1 ADMINISTERING PHENYLALANINE AMIDE DERIVATIVES (SUCH AS S-ETHYL-2-AMINO-3-(4-CHLOROPHENYL)PROPIONATE HYDROCHLORIDE) TO TREAT ALLERGIC DISORDERS, INCLUDING ASTHMA, RHINITIS, DERMATITUS, AND PRURITIS SMITHKLINE BEECHAM CORPORATION 2002-07-16 US claimed
JP-2002512960-A 2002-05-08 JP claimed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 US claimed
EP-1073434-A1 CCR-3 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 2001-02-07 EP claimed
US-6143517-A Thermostable proteolytic enzymes and uses thereof in peptide and protein synthesis UNIVERSITY OF FLORIDA (US) 2000-11-07 US claimed
WO-1999055330-A1 CCR-3 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1999-11-04 WO claimed
EP-0105092-A2 A thrombolytic agent Amano Seiyaku Kabushiki Kaisha (JP) 1984-04-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358647-A1 Protease Inhibitor-Containing Compositions, Compositions Comprising Same, and Methods for Producing and Using Same SPINT2, CTRL, PREP CTSL 39/4885GAA 195/4885RAB9A 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.