Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthene SCHEMBL27837879 | 0.83 | MAOA (0.85) | MAOAMAOBACSL1GAANPSR1 | |
| SCHEMBL9455528 | 0.81 | MAOA (0.81) | MAOAMAOBACSL1GAANPSR1 | |
| Xanthene SCHEMBL9339684 | 0.81 | MAOA (1.00) | MAOAMAOBACSL1GAANPSR1 | |
| Xanthene SCHEMBL30586075 | 0.81 | MAOA (1.00) | MAOAMAOBACSL1GAANPSR1 | |
| Xanthene SCHEMBL29378346 | 0.81 | MAOA (1.00) | MAOAMAOBACSL1GAANPSR1 | |
| Xanthene SCHEMBL27493963 | 0.81 | MAOA (1.00) | MAOAMAOBACSL1GAANPSR1 | |
| Xanthene SCHEMBL4267 | 0.81 | MAOA (1.00) | MAOAMAOBACSL1GAANPSR1 | |
| SCHEMBL9455608 | 0.79 | MAOA (0.77) | MAOAMAOBACSL1GAANPSR1 | |
| Xanthene SCHEMBL27942350 | 0.79 | MAOA (0.85) | MAOAMAOBACSL1GAANPSR1 | |
| Xanthene SCHEMBL23355281 | 0.79 | MAOA (0.94) | MAOAMAOBACSL1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692053-A1 | IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019070643-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-11 | — | — | WO | disclosed |
| EP-3423470-A1 | IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-3233887-A1 | IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016126646-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-08-11 | — | — | WO | disclosed |
| WO-2016100608-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-06-23 | — | — | WO | disclosed |