Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845401 | 0.78 | PARG (0.38) | PARGPOLB | |
| SCHEMBL17845404 | 0.68 | PARG (0.68) | PARG | |
| SCHEMBL31122052 | 0.60 | PARG (0.68) | PARG | |
| SCHEMBL17845484 | 0.59 | PARG (0.70) | PARG | |
| SCHEMBL17845403 | 0.56 | PARG (0.67) | PARG | |
| SCHEMBL31122072 | 0.56 | PARG (0.67) | PARG | |
| SCHEMBL282282 | 0.55 | CA1 (0.41) | — | |
| SCHEMBL16908459 | 0.53 | CA1 (0.35) | — | |
| SCHEMBL19748545 | 0.53 | CA1 (0.43) | — | |
| SCHEMBL6180421 | 0.53 | SOS1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233845-A1 | PARG INHIBITORY COMPOUNDS | Cancer Research Technology Limited (GB) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097749-A1 | PARG INHIBITORY COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |