Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.41 |
| ▸ | CA2 | P00918 | 14/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177831 | 0.84 | CA1 (0.46) | CA1CA2CA12CA7CA13 | |
| SCHEMBL30876263 | 0.84 | CA1 (0.46) | CA1CA2CA12CA7CA13 | |
| SCHEMBL28018499 | 0.81 | CES2 (0.39) | CA1CA2CA12CA7CA13 | |
| SCHEMBL7919248 | 0.80 | ALDH1A1 (0.37) | CA1CA2CA12CA7TDP1 | |
| SCHEMBL1541882 | 0.80 | CA1 (0.41) | CA1CA2CA12CA7TDP1 | |
| SCHEMBL22919992 | 0.80 | EPAS1 (0.35) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2536209 | 0.80 | CYP3A4 (0.39) | CA1CA2CA12CA7CA13 | |
| SCHEMBL25252706 | 0.78 | VCAM1 (0.51) | CA1CA2CA12TDP1ALDH1A1 | |
| SCHEMBL30489366 | 0.78 | VCAM1 (0.51) | CA1CA2CA12TDP1ALDH1A1 | |
| SCHEMBL5151223 | 0.78 | CA1 (0.44) | CA1CA2CA12CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | claimed |
| CN-119528810-B | Quinoline compound and application thereof | 山东第一医科大学(山东省医学科学院) | 2025-04-29 | — | — | CN | disclosed |
| CN-119528810-A | Quinoline compound and application thereof | 山东第一医科大学(山东省医学科学院) | 2025-02-28 | — | — | CN | disclosed |
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2025-02-13 | — | — | US | disclosed |
| CN-119390708-A | Novel curcumenol derivative and synthetic method and application thereof | 天津中医药大学 | 2025-02-07 | — | — | CN | disclosed |
| EP-4499609-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119301096-A | Inhibitors of MYST family lysine acetyltransferase | 伊索斯泰里克斯公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119264303-A | Pendant group functionalized fluorine-containing polymer, preparation method of fluorine-containing polymer, ion exchange membrane and application | 佛山绿动氢能科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| US-12187732-B2 | Inhibitors of the myst family of lysine acetyl transferases | Isosterix, Inc. (US) | 2025-01-07 | — | — | US | disclosed |
| CN-119264026-A | Method for synthesizing cyclic sulfonamide and sulfonyl olefin by mechanical light excitation | 西北大学 | 2025-01-07 | — | — | CN | disclosed |
| US-20060199820-A1 | e.g. N1-hydroxy-N2-[(4-phenoxyphenyl)sulfonyl]-D-argininamide; metallopeptidase inhibitor; antiinflammation, anticarcinogenic, antidiabetic agent; angiogenesis inhibitor; atherosclerosis, stroke, ulcer, infertility, scleroderma, endometriosis, mesothelioma | SYMPHONY EVOLUTION, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-1656361-A1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-17 | — | — | EP | disclosed |
| US-20050227973-A1 | Human adam-10 inhibitors | EXELIXIS, INC. | 2005-10-13 | — | — | US | disclosed |
| US-20050209241-A1 | Benzoyl-piperazine derivatives | HOFFMANN-LA ROCHE INC. | 2005-09-22 | — | — | US | disclosed |
| EP-1511488-A2 | HUMAN ADAM-10 INHIBITORS | Exelixis, Inc. (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20050049286-A1 | Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS INC. | 2005-03-03 | — | — | US | disclosed |
| WO-2005014563-A1 | PIPERAZINE WITH OR-SUBSTITUTED PHENYL GROUP AND THEIR USE AS GLYT1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| EP-1461313-A1 | HUMAN ADAM-10 INHIBITORS | Exelixis, Inc. (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003106381-A2 | HUMAN ADAM-10 INHIBITORS | EXELIXIS, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003051825-A1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS, INC. (US) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209241-A1 | Benzoyl-piperazine derivatives | SLC1A2, SLC18A2, SLC6A7 | CA1 4221/4885CA2 3258/4885CA12 4755/4885 |
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | KAT6A, KAT6B, KAT2A | CA1 3845/4885CA2 4141/4885CA12 4272/4885 |
| US-12187732-B2 | Inhibitors of the myst family of lysine acetyl transferases | KAT6A, KAT6B, KAT2A | CA1 3845/4885CA2 4141/4885CA12 4272/4885 |
| US-20050227973-A1 | Human adam-10 inhibitors | ADAM10, ADAM12, ADAM9 | CA1 461/4885CA2 1016/4885CA12 497/4885 |
| US-20050049286-A1 | Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists | CCR9, CCR1, CCRL2 | CA1 2141/4885CA2 1262/4885CA12 1392/4885 |
| US-20060199820-A1 | e.g. N1-hydroxy-N2-[(4-phenoxyphenyl)sulfonyl]-D-argininamide; metallopeptidase inhibitor; antiinflammation, anticarcinogenic, antidiabetic agent; angiogenesis inhibitor; atherosclerosis, stroke, ulcer, infertility, scleroderma, endometriosis, mesothelioma | ADAM10, MMP20, MMP10 | CA1 192/4885CA2 1122/4885CA12 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.