Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845561 | 0.78 | PARG (0.37) | PARGPOLB | |
| SCHEMBL17845231 | 0.70 | PARG (0.68) | PARG | |
| SCHEMBL31122052 | 0.70 | PARG (0.68) | PARG | |
| SCHEMBL31443322 | 0.62 | AR (0.39) | — | |
| SCHEMBL17845404 | 0.60 | PARG (0.68) | PARG | |
| SCHEMBL11821445 | 0.58 | KDM4E (0.36) | PARGPOLB | |
| SCHEMBL8553555 | 0.57 | CYP11B1 (0.42) | — | |
| SCHEMBL8665535 | 0.57 | TRPV4 (0.32) | POLB | |
| SCHEMBL1094769 | 0.57 | TRPV4 (0.32) | POLB | |
| SCHEMBL320605 | 0.56 | SLC1A3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233845-A1 | PARG INHIBITORY COMPOUNDS | Cancer Research Technology Limited (GB) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097749-A1 | PARG INHIBITORY COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |