SCHEMBL17845647

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31121972	1.00	LMNA (0.68)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL7745956	0.92	LMNA (0.57)	LMNAMAPTALDH1A1HCAR3KMT2A
	SCHEMBL1420919	0.91	LMNA (0.56)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL932259	0.89	LMNA (0.68)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL12210037	0.86	LMNA (0.50)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL14616761	0.84	LMNA (0.70)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL3515437	0.84	HCAR3 (0.52)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL2552231	0.83	LMNA (0.68)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL10576590	0.83	LMNA (0.68)	LMNAMAPTALDH1A1HCAR3RAB9A
	SCHEMBL29719258	0.83	LMNA (0.68)	LMNAMAPTALDH1A1HCAR3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.