Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17846005 | 0.66 | MAPK1 (0.44) | — | |
| SCHEMBL17846154 | 0.66 | MAPK1 (0.40) | — | |
| SCHEMBL1838455 | 0.65 | ADRB1 (0.48) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL17846168 | 0.65 | MAPK1 (0.39) | — | |
| SCHEMBL17846135 | 0.64 | MAPK1 (0.42) | — | |
| SCHEMBL1837158 | 0.64 | ALDH1A1 (0.48) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL1840538 | 0.64 | ALDH1A1 (0.48) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL1838922 | 0.64 | ALDH1A1 (0.48) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL4311670 | 0.64 | ADRB1 (0.46) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL19348964 | 0.64 | MAPK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233859-A1 | ERK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100051-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-23 | — | — | WO | disclosed |