SCHEMBL1784642

SCHEMBL1784642

CCC(CC)C(CC(OC(=O)c1ccccc1)C(C)C)OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
LMNA P02545 4/20 0.44
NPC1 O15118 3/20 0.43
ALDH1A1 P00352 2/20 0.43
RAB9A P51151 2/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PRKCA P17252 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
POLB P06746 1/20 0.42
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
F2 P00734 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571244 0.92 TSHR (0.53) TSHRTP53PDCD1CD274LMNA
SCHEMBL12676586 0.88 TSHR (0.46) TSHRTP53PDCD1CD274LMNA
SCHEMBL12863873 0.87 TSHR (0.52) TSHRTP53PDCD1CD274LMNA
SCHEMBL561247 0.86 MEN1 (0.46) TSHRTP53PDCD1CD274LMNA
SCHEMBL25982607 0.85 TSHR (0.50) TSHRTP53PDCD1CD274LMNA
SCHEMBL569214 0.84 LMNA (0.50) TSHRTP53PDCD1CD274LMNA
SCHEMBL16044058 0.83 TSHR (0.45) TSHRTP53PDCD1CD274LMNA
SCHEMBL28686043 0.83 PRKCA (0.50) TSHRTP53PDCD1CD274LMNA
SCHEMBL14503025 0.83 PRKCA (0.50) TSHRTP53PDCD1CD274LMNA
SCHEMBL14690196 0.82 TSHR (0.53) TSHRTP53PDCD1CD274LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930872-A Catalyst system, prepolymerized catalyst composition and olefin polymerization process 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119930869-A Auxiliary agent for olefin polymerization, olefin catalyst system, prepolymerized catalyst composition and olefin polymerization method 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119841986-A Propylene polymer and synthetic method thereof 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-119841996-A Ethylene/propylene random polymer and synthetic method thereof 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-114426599-B Catalyst component for preparing polyolefin, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2023-11-10 CN claimed
CN-114478846-B Carrier of catalyst with olefin polymerization catalyzing function, preparation method and application thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2023-09-08 CN claimed
CN-110938161-B Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2022-05-24 CN claimed
CN-114478846-A Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-114426599-A Catalyst component for preparing polyolefin, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2022-05-03 CN claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US claimed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
CN-116854848-B Preparation method of ultra-high molecular weight poly alpha-olefin 金浦新材料股份有限公司 2026-05-19 CN disclosed
CN-119930869-A Auxiliary agent for olefin polymerization, olefin catalyst system, prepolymerized catalyst composition and olefin polymerization method 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119930872-A Catalyst system, prepolymerized catalyst composition and olefin polymerization process 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119841986-A Propylene polymer and synthetic method thereof 中国石油化工股份有限公司 2025-04-18 CN disclosed
US-7332455-B2 Catalyst component and catalyst for olefin polymerization as well as use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-02-19 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed