Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572607 | 0.81 | MAPT (0.62) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL5940992 | 0.79 | ALDH1A1 (0.56) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL2516508 | 0.77 | ALDH1A1 (0.67) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL12724392 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAGAAATM | |
| Water SCHEMBL27691964 | 0.75 | ALDH1A1 (0.65) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL10700016 | 0.75 | MAPT (0.51) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL10778948 | 0.74 | POLB (0.53) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL11301646 | 0.73 | MEN1 (0.54) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL9886 | 0.73 | ALDH1A1 (0.85) | MAPTALDH1A1LMNAGAAATM | |
| SCHEMBL4296111 | 0.73 | MAPT (0.85) | MAPTALDH1A1LMNAGAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233800-A2 | LIGAND COMPONENTS, ASSOCIATED REACTION PRODUCTS, ACTIVATED REACTION PRODUCTS, HYDROSILYLATION CATALYSTS AND HYDROSILYLATION CURABLE COMPOSITIONS INCLUDING THE LIGAND COMPONENTS, AND ASSOCIATED METHODS FOR PREPARING SAME | Dow Corning Corporation (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016099727-A2 | LIGAND COMPONENTS, ASSOCIATED REACTION PRODUCTS, ACTIVATED REACTION PRODUCTS, HYDROSILYLATION CATALYSTS AND HYDROSILYLATION CURABLE COMPOSITIONS INCLUDING THE LIGAND COMPONENTS, AND ASSOCIATED METHODS FOR PREPARING SAME | DOW CORNING CORPORATION (US) | 2016-06-23 | — | — | WO | disclosed |