SCHEMBL2516508

SCHEMBL2516508

CC(Cl)C(=O)Nc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
MAPT P10636 4/20 0.67
GAA P10253 4/20 0.67
ATM Q13315 3/20 0.67
LMNA P02545 1/20 0.67
HSP90AA1 P07900 2/20 0.65
RAB9A P51151 2/20 0.65
NPC1 O15118 1/20 0.65
GPR55 Q9Y2T6 2/20 0.62
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
HPGD P15428 2/20 0.61
HTT P42858 2/20 0.61
RXFP1 Q9HBX9 1/20 0.61
POLB P06746 1/20 0.57
NAPRT Q6XQN6 1/20 0.54
HSD17B10 Q99714 1/20 0.54
NPSR1 Q6W5P4 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27691964 0.98 ALDH1A1 (0.65) ALDH1A1MAPTGAAATMLMNA
SCHEMBL3683038 0.89 MAPT (0.53) ALDH1A1MAPTGAAATMLMNA
SCHEMBL10696484 0.84 SMN1; SMN2 (0.62) ALDH1A1RAB9ANPC1SMN1; SMN2HPGD
SCHEMBL10572607 0.84 MAPT (0.62) ALDH1A1MAPTGAAATMLMNA
SCHEMBL9886 0.83 ALDH1A1 (0.85) ALDH1A1MAPTGAAATMLMNA
SCHEMBL18852431 0.83 ALDH1A1 (0.66) ALDH1A1MAPTGAAATMLMNA
SCHEMBL19425986 0.83 ALDH1A1 (0.85) ALDH1A1MAPTGAAATMLMNA
SCHEMBL4296111 0.83 MAPT (0.85) ALDH1A1MAPTGAAATMLMNA
SCHEMBL11516582 0.82 ALDH1A1 (0.53) ALDH1A1MAPTGAAATMLMNA
SCHEMBL10897100 0.82 L3MBTL1 (0.56) ALDH1A1MAPTGAAATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214139-B Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof 江苏谛奇医药科技有限公司 2022-03-04 CN claimed
CN-113214139-A Piperidine amide derivative, preparation method thereof, pharmaceutical composition thereof, single crystal culture method thereof and application thereof 江苏谛奇医药科技有限公司 2021-08-06 CN claimed
CN-104119266-A Method for preparing carbazole from phenolic compound UNIV ZHEJIANG 2014-10-29 CN claimed
US-7651747-B2 Fusible inkjet media including solid plasticizer particles and methods of forming and using the fusible inkjet media HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2010-01-26 US claimed
EP-1629988-B1 Fusible inkjet media including solid plasticizer particles and methods of forming and using the fusible inkjet media HEWLETT PACKARD DEVELOPMENT CO (US) 2008-12-24 EP claimed
EP-1629988-A2 Fusible inkjet media including solid plasticizer particles and methods of forming and using the fusible inkjet media Hewlett-Packard Development Company, L.P. (US) 2006-03-01 EP claimed
US-20060038871-A1 Fusible inkjet media including solid plasticizer particles and methods of forming and using the fusible inkjet media HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-02-23 US claimed
CN-1043402-C Herbicide tablets or capsules for paddy field application by throwing them into water ISHIHARA SANGYO KAISHA (JP) 1999-05-19 CN claimed
CN-1049951-A The weeding tablet or the capsule of paddy field application by throwing them ISHIHARA SANGYO KAISHA (JP) 1991-03-20 CN claimed
US-4096333-A NITROSATION OF A 2-METHYLACETANILIDE TENNECO CHEMICALS, INC. (US) 1978-06-20 US claimed
JP-2255648-A None JP disclosed
US-12576662-B2 Thermographic imaging element INTERNATIONAL IMAGING MATERIALS, INC. (US) 2026-03-17 US disclosed
EP-4359219-A1 THERMOGRAPHIC IMAGING ELEMENT International Imaging Materials Inc. (US) 2024-05-01 EP disclosed
US-20240094619-A1 THERMOGRAPHIC IMAGING ELEMENT INTERNATIONAL IMAGING MATERIALS, INC. (US) 2024-03-21 US disclosed
WO-2022271595-A1 THERMOGRAPHIC IMAGING ELEMENT INTERNATIONAL IMAGING MATERIALS, INC. (US) 2022-12-29 WO disclosed
US-4499100-A CARDIOUVASCULAR DISORDERS SYNTEX (U.S.A.) INC. (US) 1985-02-12 US disclosed
EP-0126449-A1 Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry SYNTEX (U.S.A.) INC. (US) 1984-11-28 EP disclosed
EP-0053495-A1 Process for producing N-(halomethyl) acylamides MONSANTO COMPANY (US) 1982-06-09 EP disclosed
US-4096333-A NITROSATION OF A 2-METHYLACETANILIDE TENNECO CHEMICALS, INC. (US) 1978-06-20 US disclosed
US-3988347-A NITROSATION OF A 2-METHYL-ACETANILIDE WITH SODIUM NITRITE TENNECO CHEMICALS, INC. (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576662-B2 Thermographic imaging element TPR, TAGLN2, FLNB ALDH1A1 4375/4885MAPT 9/4885GAA 4674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.