Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 19/20 | 0.51 |
| ▸ | IL17A | Q16552 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17843833 | 0.87 | VCAM1 (0.59) | MEN1ALDH1A1KMT2ARORCIL17A | |
| SCHEMBL17858289 | 0.86 | RORC (0.52) | RORCIL17A | |
| SCHEMBL17843345 | 0.84 | RORC (0.49) | RORCIL17A | |
| SCHEMBL17843945 | 0.80 | RORC (0.56) | RORCIL17A | |
| SCHEMBL17858304 | 0.79 | RORC (0.55) | RORCIL17A | |
| SCHEMBL17852447 | 0.78 | RORC (0.54) | RORCIL17A | |
| SCHEMBL17843316 | 0.78 | RORC (0.50) | RORCIL17A | |
| SCHEMBL17843315 | 0.78 | RORC (0.50) | RORCIL17A | |
| SCHEMBL17843934 | 0.78 | RORC (0.61) | RORCIL17A | |
| SCHEMBL20677666 | 0.77 | RORC (0.51) | RORCIL17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097394-A1 | BICYCLIC SULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T)) | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097394-A1 | BICYCLIC SULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T)) | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-23 | — | — | WO | disclosed |