Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CHIT1 | Q13231 | 5/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | CCR3 | P51677 | 7/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421074 | 0.89 | CHIT1 (0.42) | FAAHCHIT1CHIAKCNH2CCR3 | |
| SCHEMBL17838837 | 0.88 | CHRM1 (0.49) | FAAHCHIT1CHIAKCNH2SMN1; SMN2 | |
| SCHEMBL17847360 | 0.84 | FAAH (0.45) | FAAHCHIT1CHIAKCNH2CCR3 | |
| Hydrochloric Acid SCHEMBL17838892 | 0.83 | FAAH (0.44) | FAAHCHIT1CHIAKCNH2CCR3 | |
| SCHEMBL17838885 | 0.82 | KCNH2 (0.44) | FAAHCHIT1CHIAKCNH2NR1D1 | |
| SCHEMBL28174775 | 0.68 | MEN1 (0.58) | NR1D1MEN1KMT2AGPR119SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28430234 | 0.67 | CHIT1 (0.49) | CHIT1CHIAKCNH2CCR3MEN1 | |
| SCHEMBL17838844 | 0.66 | C5AR1 (0.49) | CHIT1CHIAKCNH2CCR3MEN1 | |
| SCHEMBL17838866 | 0.64 | MEN1 (0.49) | CHIT1CHIAKCNH2CCR3NR1D1 | |
| SCHEMBL17838900 | 0.64 | MEN1 (0.49) | CHIT1CHIAKCNH2CCR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233832-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS S.A. (PL) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016099311-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | WO | disclosed |