Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648962 | 0.86 | IKBKB (0.49) | IKBKBRARAMEN1KMT2AALDH1A1 | |
| SCHEMBL8648956 | 0.80 | IKBKB (0.33) | IKBKBRARA | |
| SCHEMBL852015 | 0.79 | RARA (0.42) | RARAEPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL9318559 | 0.77 | HDAC11 (0.41) | RARAEPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL17847406 | 0.76 | RARA (0.42) | IKBKBRARAEPHX2MEN1KMT2A | |
| SCHEMBL8648960 | 0.75 | — | — | |
| SCHEMBL25330683 | 0.74 | EPHX2 (0.34) | IKBKBRARAEPHX2MEN1KMT2A | |
| SCHEMBL19639512 | 0.73 | RARA (0.43) | IKBKBRARAEPHX2MEN1KMT2A | |
| SCHEMBL8457849 | 0.73 | RARA (0.47) | IKBKBRARAEPHX2MEN1KMT2A | |
| SCHEMBL23071384 | 0.71 | ALDH1A1 (0.38) | RARAEPHX2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233806-B1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RES & DEV (FR) | 2021-10-27 | — | — | EP | disclosed |
| EP-3233806-A1 | NOVEL COMPOUNDS, SYNTHESIS METHOD THEREOF AND USE OF SAME IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016097626-A1 | NOVEL COMPOUNDS, SYNTHESIS METHOD THEREOF AND USE OF SAME IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-23 | — | — | WO | disclosed |