SCHEMBL17847474

SCHEMBL17847474

CCc1ccc(N=C=O)c(Sc2ccccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GABRA1 P14867 1/20 0.36
▸ GABRB2 P47870 1/20 0.36
▸ LMNA P02545 3/20 0.34
▸ TP53 P04637 2/20 0.34
▸ RXFP1 Q9HBX9 1/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP2A6 P11509 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ SLC6A4 P31645 3/20 0.34
▸ SLC6A2 P23975 2/20 0.34
▸ HPGD P15428 2/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19712993 0.89 HTR2C (0.34) GABRA1GABRB2ALDH1A1CYP3A4SLC6A4
SCHEMBL10987291 0.87 CYP3A4 (0.44) GABRA1GABRB2ALDH1A1CYP3A4CYP1A2
SCHEMBL19712976 0.87 CYP3A4 (0.35) ALDH1A1CYP3A4CYP1A2HPGD
SCHEMBL28471916 0.82 HPGD (0.43) GABRA1GABRB2TP53CYP3A4SLC6A4
SCHEMBL17847448 0.82 CYP3A4 (0.33) GABRA1GABRB2ALDH1A1CYP3A4SLC6A4
SCHEMBL17847501 0.81 CYP3A4 (0.41) LMNATP53ALDH1A1CYP3A4L3MBTL1
SCHEMBL19712975 0.79 SLC6A4 (0.38) TP53ALDH1A1CYP3A4NPC1MAPT
SCHEMBL19712969 0.78 PDE7A (0.47) LMNAL3MBTL1MAPK1SLC6A4SLC6A2
SCHEMBL19712961 0.78 ALDH1A1 (0.38) ALDH1A1CYP3A4L3MBTL1CYP1A2MAPT
SCHEMBL624408 0.76 CYP3A4 (0.44) LMNAALDH1A1CYP3A4L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107223121-B Wet stable holographic media 科思创德国股份有限公司 2020-10-27 — — CN disclosed
EP-3233791-B1 MOISTURE STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2020-08-12 — — EP disclosed
US-10329244-B2 Moisture-stable holographic media COVESTRO DEUTSCHLAND AG (DE) 2019-06-25 — — US disclosed
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 — — US disclosed
EP-3233791-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA Covestro Deutschland AG (DE) 2017-10-25 — — EP disclosed
WO-2016096641-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2016-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10329244-B2 Moisture-stable holographic media NEFM, MDM4, BHMT2 GABRA1 4791/4885GABRB2 4845/4885LMNA 3651/4885
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA NEFM, MDM4, BHMT2 GABRA1 4791/4885GABRB2 4845/4885LMNA 3651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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