SCHEMBL17847495

SCHEMBL17847495

O=C=Nc1ccccc1Sc1ccccc1Br

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
CYP3A4 P08684 2/20 0.41
PDE7A Q13946 4/20 0.39
PDE7B Q9NP56 2/20 0.38
LDHA P00338 1/20 0.33
HTR7 P34969 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8937141 0.89 CYP3A4 (0.50) CYP3A4TRPA1
SCHEMBL29808667 0.89 CYP3A4 (0.50) CYP3A4TRPA1
SCHEMBL17847454 0.79 CYP3A4 (0.41) LMNACYP3A4LDHATRPA1
SCHEMBL17847456 0.79 CYP3A4 (0.41) LMNACYP3A4MAOAMAOB
SCHEMBL19713002 0.79 CYP3A4 (0.41) LMNACYP3A4LDHA
SCHEMBL17847466 0.79 CYP3A4 (0.41) CYP3A4TRPA1
SCHEMBL17847498 0.79 CYP3A4 (0.50) CYP3A4TRPA1
SCHEMBL93220 0.78 CYP3A4 (0.52) CYP3A4TRPA1
SCHEMBL29463737 0.78 CYP3A4 (0.52) CYP3A4TRPA1
SCHEMBL624408 0.78 CYP3A4 (0.44) LMNACYP3A4MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107223121-B Wet stable holographic media 科思创德国股份有限公司 2020-10-27 CN disclosed
EP-3233791-B1 MOISTURE STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2020-08-12 EP disclosed
US-10329244-B2 Moisture-stable holographic media COVESTRO DEUTSCHLAND AG (DE) 2019-06-25 US disclosed
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed
EP-3233791-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA Covestro Deutschland AG (DE) 2017-10-25 EP disclosed
WO-2016096641-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10329244-B2 Moisture-stable holographic media NEFM, MDM4, BHMT2 LMNA 3651/4885CYP3A4 3992/4885PDE7A 4117/4885
US-20170362165-A1 MOISTURE-STABLE HOLOGRAPHIC MEDIA NEFM, MDM4, BHMT2 LMNA 3651/4885CYP3A4 3992/4885PDE7A 4117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.