SCHEMBL8937141

SCHEMBL8937141

O=C=Nc1ccccc1Sc1ccccc1N=C=O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.50
TRPA1 O75762 1/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29808667 1.00 CYP3A4 (0.50) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL17847454 0.89 CYP3A4 (0.41) CYP3A4TRPA1ALDH1A1
SCHEMBL17847498 0.89 CYP3A4 (0.50) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL19713002 0.89 CYP3A4 (0.41) CYP3A4HPGDTDP1
SCHEMBL17847466 0.89 CYP3A4 (0.41) CYP3A4TRPA1
SCHEMBL17847495 0.89 LMNA (0.44) CYP3A4TRPA1
SCHEMBL17847456 0.89 CYP3A4 (0.41) CYP3A4ALDH1A1HPGDTDP1
SCHEMBL624408 0.88 CYP3A4 (0.44) CYP3A4ALDH1A1HPGDTDP1
SCHEMBL29716699 0.86 CYP3A4 (0.50) CYP3A4TRPA1GABRA1GABRB2ALDH1A1
SCHEMBL10408265 0.86 CYP3A4 (0.50) CYP3A4TRPA1GABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113631612-B Resin composition for optical member, and spectacle lens 豪雅镜片泰国有限公司 2024-03-15 CN disclosed
EP-0670756-A4 WATER-BORNE COMPOSITIONS COMPRISING HALF ESTERS OF ANHYDRIDE POLYMERS CROSSLINKED BY EPOXIES. DU PONT (US) 1996-08-21 EP disclosed
EP-0669955-A4 AN ANHYDRIDE-EPOXY COATING COMPOSITION MODIFIED WITH A SILANE POLYMER. DU PONT (US) 1996-08-07 EP disclosed
EP-0669954-A4 AN ACID-EPOXY-MELAMINE COATING COMPOSITION MODIFIED WITH A SILANE POLYMER. DU PONT (US) 1995-11-08 EP disclosed
EP-0670756-A1 WATER-BORNE COMPOSITIONS COMPRISING HALF ESTERS OF ANHYDRIDE POLYMERS CROSSLINKED BY EPOXIES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-13 EP disclosed
EP-0669954-A1 AN ACID-EPOXY-MELAMINE COATING COMPOSITION MODIFIED WITH A SILANE POLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-06 EP disclosed
EP-0669955-A1 AN ANHYDRIDE-EPOXY COATING COMPOSITION MODIFIED WITH A SILANE POLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-09-06 EP disclosed
EP-0407994-B1 Lightweight flexible imide foam and method of producing same MANVILLE CORP (US) 1995-06-28 EP disclosed
US-5376706-A Clear protective coatings E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-27 US disclosed
US-5376704-A Clearcoats with improved environmental resistance E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-27 US disclosed
US-4203875-A CURED POLYURETHANE PROTECTIVE COATING GROW CHEMICAL CORP. (US) 1980-05-20 US disclosed
US-4186117-A Cathodic electrodeposition coating compositions containing diels-alder adducts GROW CHEMICAL CORP. (US) 1980-01-29 US disclosed
US-4169955-A GRAFT POLYMER INTERMEDIATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-10-02 US disclosed
US-4155824-A ACRYLIC POLYMER CONTAINING OXIRANE GROUPS WHICH HAVE BEEN OPENED WITH A FATTY ACID AND AN AMINE GROW CHEMICAL CORP. (US) 1979-05-22 US disclosed
US-4151227-A Acrylic graft copolymers and coating compositions thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-24 US disclosed
US-4148704-A ADHESION, CORROSION RESISTANCE, GLOSS GROW CHEMICAL CORP. (US) 1979-04-10 US disclosed
US-4142927-A ISOCYANATES, OLEFINS OR IODINE AS SCAVENGERS WALKER FRANKLIN E 1979-03-06 US disclosed
US-4070509-A APPLYING POLYURETHANE COATING TO SUBSTRATE AND CURING SAME GROW CHEMICAL CORPORATION (US) 1978-01-24 US disclosed
US-3998768-A Thermosetting powder coating composition of a blend of acrylic polymers having different glass transition temperatures and a blocked polyisocyanate cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-21 US disclosed
US-3969569-A ALLYL ALCOHOL POLYMER AND A POLYISOCYANATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-13 US disclosed