Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905134 | 0.94 | ALDH1A1 (0.64) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL13224766 | 0.87 | ALDH1A1 (0.49) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL3172976 | 0.87 | TP53 (0.49) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL8854472 | 0.84 | HRH3 (0.41) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL8062950 | 0.83 | ALOX15 (0.60) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL7793237 | 0.82 | ALDH1A1 (0.50) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL7793231 | 0.82 | ALDH1A1 (0.50) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL24197395 | 0.81 | MAOB (0.59) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL6056697 | 0.81 | ALOX15 (0.58) | MAOBALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL11228368 | 0.81 | ALDH1A1 (0.88) | MAOBALDH1A1TP53CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107109221-B | Bimesogenic compounds and mesogenic media | 默克专利股份有限公司 | 2021-03-12 | — | — | CN | disclosed |
| EP-3257839-B1 | POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| EP-3173457-B1 | LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2019-06-05 | — | — | EP | disclosed |
| EP-3234065-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-09-26 | — | — | EP | disclosed |
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| EP-3234065-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | Merck Patent GmbH (DE) | 2017-10-25 | — | — | EP | disclosed |
| US-20170218271-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | DIC CORPORATION (JP) | 2017-08-03 | — | — | US | disclosed |
| EP-3173457-A1 | LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME | DIC Corporation (JP) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016096112-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016096112-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327741-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | MAOB 3274/4885ALDH1A1 4654/4885TP53 1989/4885 |
| US-10392561-B2 | Bimesogenic compounds and mesogenic media | SP1, FOXM1, S100A11 | MAOB 3274/4885ALDH1A1 4654/4885TP53 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.