Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13107005 | 0.90 | LTA4H (0.55) | SLC6A2SLC6A4SLC6A3TDP1LTA4H | |
| SCHEMBL3251238 | 0.90 | TDP1 (0.68) | SLC6A2SLC6A4SLC6A3TDP1LTA4H | |
| SCHEMBL2069683 | 0.86 | LTA4H (0.51) | SLC6A2SLC6A4SLC6A3LTA4HKDM1A | |
| SCHEMBL21618374 | 0.83 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3TDP1HTR3A | |
| SCHEMBL21398105 | 0.83 | SLC6A4 (0.61) | SLC6A2SLC6A4SLC6A3TDP1LTA4H | |
| SCHEMBL35429 | 0.83 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3TDP1LTA4H | |
| SCHEMBL27972144 | 0.83 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3TDP1LTA4H | |
| SCHEMBL935709 | 0.83 | NPY1R (0.50) | SLC6A2SLC6A4 | |
| SCHEMBL935234 | 0.83 | NPY1R (0.50) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL20893519 | 0.82 | SLC6A4 (0.60) | SLC6A2SLC6A4SLC6A3TDP1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4474017-A2 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2024-12-11 | — | — | EP | disclosed |
| EP-3837263-B1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2024-07-03 | — | — | EP | disclosed |
| EP-3233077-A1 | DOPAMINE D2 RECEPTOR LIGANDS | The Broad Institute Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100940-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2016-06-23 | — | — | WO | disclosed |