Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 15/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935234 | 1.00 | NPY1R (0.50) | NPY1RITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL28283793 | 0.91 | NPY1R (0.57) | NPY1R | |
| SCHEMBL7956507 | 0.85 | ITGB3 (0.46) | NPY1RITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL4326032 | 0.83 | NPY1R (0.50) | NPY1RITGB3ITGA2B | |
| SCHEMBL17848466 | 0.83 | SLC6A2 (0.61) | SLC6A2SLC6A4 | |
| SCHEMBL997318 | 0.81 | ITGB3 (0.42) | NPY1RITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL5185586 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL2299161 | 0.79 | NFE2L2 (0.44) | SLC6A4 | |
| SCHEMBL2890073 | 0.78 | SLC6A2 (0.47) | NPY1RITGB3ITGA2BSLC6A2SLC6A4 | |
| SCHEMBL16825941 | 0.78 | HRH3 (0.49) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454234-A2 | 3-PHENOXYMETHYLPYRROLIDINE COMPOUNDS | Theravance, Inc. (US) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011008666-A2 | 3-PHENOXYMETHYLPYRROLIDINE COMPOUNDS | THERAVANCE, INC. (US) | 2011-01-20 | — | — | WO | disclosed |