Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848671 | 0.75 | USP2 (0.47) | USP2ALDH1A1 | |
| SCHEMBL28379744 | 0.75 | CTSD (0.34) | USP2 | |
| SCHEMBL15759336 | 0.73 | FFAR3 (0.38) | OPRM1USP2ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL20738595 | 0.73 | OPRM1 (0.39) | OPRM1OPRL1CYP2C19FFAR3 | |
| SCHEMBL20738603 | 0.73 | OPRM1 (0.39) | OPRM1OPRL1ALDH1A1CYP2C19FFAR3 | |
| SCHEMBL19641323 | 0.72 | FFAR3 (0.39) | USP2ALDH1A1MAPK1CYP2C19FFAR3 | |
| SCHEMBL4539328 | 0.72 | OPRM1 (0.32) | OPRM1OPRL1 | |
| SCHEMBL3646525 | 0.72 | OPRM1 (0.32) | OPRM1OPRL1 | |
| SCHEMBL24272639 | 0.72 | OPRM1 (0.38) | OPRM1OPRL1ALDH1A1FFAR3 | |
| SCHEMBL14501954 | 0.72 | OPRM1 (0.38) | OPRM1OPRL1ALDH1A1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233077-A1 | DOPAMINE D2 RECEPTOR LIGANDS | The Broad Institute Inc. (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016100940-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2016-06-23 | — | — | WO | disclosed |