SCHEMBL178486

SCHEMBL178486

Oc1ccc(C2CCC(O)CC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 19/20 1.00
ESR1 P03372 7/20 0.61
CYP3A4 P08684 2/20 0.61
CYP2C9 P11712 2/20 0.61
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL605342 1.00 ESR2 (1.00) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL18257876 0.92 ESR2 (1.00) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL16743001 0.92 ESR2 (1.00) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL18257875 0.92 ESR2 (1.00) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL3809909 0.90 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL1865798 0.90 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL1986271 0.90 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL3811445 0.90 ESR2 (0.81) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL31574441 0.85 ESR2 (0.74) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL29156158 0.85 ESR2 (0.74) ESR2ESR1CYP3A4CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3071541-B1 SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM UNIV MARQUETTE (US) 2023-06-07 EP claimed
CN-106892805-B Synthesis method of 4- (4-hydroxyphenyl) cyclohexanone 西安瑞联新材料股份有限公司 2021-02-23 CN claimed
CN-112341320-A Novel synthesis method of p- (trans-4-hydroxycyclohexyl) phenol 烟台丰鲁精细化工有限责任公司 2021-02-09 CN claimed
EP-0303398-B1 PREPARATION PROCESS OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-11 EP claimed
US-4894487-A Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-01-16 US claimed
JP-1047727-A None JP disclosed
JP-1160930-A None JP disclosed
CN-120019088-A Vinyl compound, vinyl composition, cured vinyl resin, prepreg, resin-coated film, resin-coated metal foil, metal-clad laminate, and printed wiring board 住友化学株式会社 2025-05-16 CN disclosed
WO-2025094673-A1 VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, FILM WITH RESIN, METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD 住友化学株式会社 2025-05-08 WO disclosed
WO-2024122295-A1 VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, FILM WITH RESIN, METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD 住友化学株式会社 2024-06-13 WO disclosed
WO-2024085082-A1 VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, RESIN-ATTACHED FILM, RESIN-ATTACHED METAL FOIL, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD 住友化学株式会社 2024-04-25 WO disclosed
EP-3071541-B1 SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM UNIV MARQUETTE (US) 2023-06-07 EP disclosed
US-4894487-A Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-01-16 US disclosed
US-4894487-A Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-01-16 US disclosed
US-4894487-A Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-01-16 US disclosed
JP-H01160930-A PRODUCTION OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL AND 4,4'-BIPHENOL MITSUI TOATSU CHEM INC 1989-06-23 JP disclosed
JP-S6447727-A PRODUCTION OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL MITSUI TOATSU CHEMICALS 1989-02-22 JP disclosed
EP-0303398-A1 Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-02-15 EP disclosed
EP-0303398-A1 Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-02-15 EP disclosed
EP-0303398-A1 Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-02-15 EP disclosed