Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 1.00 |
| ▸ | ESR1 | P03372 | 7/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178486 | 1.00 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18257876 | 0.92 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL16743001 | 0.92 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18257875 | 0.92 | ESR2 (1.00) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3809909 | 0.90 | ESR2 (0.81) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL1865798 | 0.90 | ESR2 (0.81) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL1986271 | 0.90 | ESR2 (0.81) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3811445 | 0.90 | ESR2 (0.81) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL31574441 | 0.85 | ESR2 (0.74) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL29156158 | 0.85 | ESR2 (0.74) | ESR2ESR1CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341320-A | Novel synthesis method of p- (trans-4-hydroxycyclohexyl) phenol | 烟台丰鲁精细化工有限责任公司 | 2021-02-09 | — | — | CN | claimed |
| CN-120019086-A | Vinyl compound, vinyl composition, cured vinyl resin, prepreg, resin-coated film, resin-coated metal foil, metal-clad laminate, and printed wiring board | 住友化学株式会社 | 2025-05-16 | — | — | CN | disclosed |
| CN-120019088-A | Vinyl compound, vinyl composition, cured vinyl resin, prepreg, resin-coated film, resin-coated metal foil, metal-clad laminate, and printed wiring board | 住友化学株式会社 | 2025-05-16 | — | — | CN | disclosed |
| WO-2025094673-A1 | VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, FILM WITH RESIN, METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD | 住友化学株式会社 | 2025-05-08 | — | — | WO | disclosed |
| US-20240327421-A1 | Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation | CU Ventures, Inc. | 2024-10-03 | — | — | US | disclosed |
| WO-2024122295-A1 | VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, FILM WITH RESIN, METAL FOIL WITH RESIN, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD | 住友化学株式会社 | 2024-06-13 | — | — | WO | disclosed |
| WO-2024085082-A1 | VINYL COMPOUND, VINYL COMPOSITION, VINYL RESIN CURED PRODUCT, PREPREG, RESIN-ATTACHED FILM, RESIN-ATTACHED METAL FOIL, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD | 住友化学株式会社 | 2024-04-25 | — | — | WO | disclosed |
| EP-3071541-B1 | SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM | UNIV MARQUETTE (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20210340155-A1 | Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation | CU Ventures, Inc. | 2021-11-04 | — | — | US | disclosed |
| CN-112341320-A | Novel synthesis method of p- (trans-4-hydroxycyclohexyl) phenol | 烟台丰鲁精细化工有限责任公司 | 2021-02-09 | — | — | CN | disclosed |
| WO-2009158483-A1 | MESOGEN CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009012125-A1 | COMPOUNDS AND METHODS FOR MODULATING FXR | ELI LILLY AND COMPANY (US) | 2009-01-22 | — | — | WO | disclosed |
| EP-0983225-B1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | ROLIC AG (CH) | 2003-12-17 | — | — | EP | disclosed |
| US-6395351-B1 | MIXTURE; OPTICS | ROLIC AG (CH) | 2002-05-28 | — | — | US | disclosed |
| JP-2001089413-A | METHOD OF PRODUCING trans-4-(4'-OXOCYCLOHEXYL) CYCLOHEXANOLS | HONSHU CHEM IND CO LTD | 2001-04-03 | — | — | JP | disclosed |
| EP-0983225-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | Rolic AG (CH) | 2000-03-08 | — | — | EP | disclosed |
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1998052905-A1 | NEW POLYMERISABLE LIQUID CRYSTALLINE COMPOUNDS | ROLIC AG (CH) | 1998-11-26 | — | — | WO | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340155-A1 | Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation | ESR2, GPER1, ESR1 | ESR2 1/4885ESR1 3/4885CYP3A4 1012/4885 |
| US-20240327421-A1 | Substituted (4-Hydroxyphenyl)Cycloalkane and (4-Hydroxyphenyl)Cycloalkene Compounds and Uses Thereof as Selective Agonists of the Estrogen Receptor Beta Isoform for Enhanced Memory Consolidation | ESR2, GPER1, ESR1 | ESR2 1/4885ESR1 3/4885CYP3A4 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.