Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 6/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17849025 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL3747440 | 0.89 | MME (0.45) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17860525 | 0.88 | MAPT (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17848960 | 0.85 | MME (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17848959 | 0.85 | MME (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17849018 | 0.83 | MCL1 (0.39) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17849016 | 0.83 | MCL1 (0.39) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17848976 | 0.82 | ALDH1A1 (0.35) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17848978 | 0.82 | ALDH1A1 (0.35) | ALDH1A1MAPTLMNAPTGS2TDP1 | |
| SCHEMBL17848975 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNAPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001412-B | Compounds of the N-acylamino-amide family, compositions containing them and uses | 莱雅公司 | 2021-03-12 | — | — | CN | disclosed |
| EP-3233886-B1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | OREAL (FR) | 2020-02-26 | — | — | EP | disclosed |
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
| EP-3233886-A1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'Oréal (FR) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096804-A1 | COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | L'OREAL (FR) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360667-A1 | NEW COMPOUNDS IN THE FAMILY OF N-ACYLAMINO-AMIDES, COMPOSITIONS COMPRISING THEM, AND USES | H1-0, CRY1, CCNA1 | ALDH1A1 736/4885MAPT 3886/4885LMNA 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.