Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12545055 | 1.00 | ESR2 (0.37) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL12587556 | 0.98 | ESR2 (0.38) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL1108695 | 0.96 | ALDH1A1 (0.38) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL16449477 | 0.94 | ALDH1A1 (0.37) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL12878725 | 0.93 | ESR2 (0.37) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL4407792 | 0.89 | MAPT (0.38) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL10330360 | 0.86 | ESR2 (0.40) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL19413012 | 0.86 | NPC1 (0.31) | ALDH1A1MAPTNPC1HSD17B10GFER | |
| SCHEMBL12587555 | 0.85 | NPC1 (0.35) | ESR2ALDH1A1MAPTNPC1HSD17B10 | |
| SCHEMBL12824879 | 0.85 | NPC1 (0.33) | ESR2ALDH1A1MAPTNPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170100607-A1 | FIBERS IN THERAPY AND COSMETICS | MERCK PATENT GMBH (DE) | 2017-04-13 | — | — | US | disclosed |
| US-9539438-B2 | Fibers in therapy and cosmetics | MERCK PATENT GMBH (DE) | 2017-01-10 | — | — | US | disclosed |
| US-9373807-B2 | Radiative fibers | MERCK PATENT GMBH (DE) | 2016-06-21 | — | — | US | disclosed |