Sugi Predict

Sugi Predict / Compounds / SCHEMBL10330360

SCHEMBL10330360

SCHEMBL10330360

Cc1ccc(-c2ccc(-c3ccc(-c4ccc(C)c5nsnc45)s3)s2)c2nsnc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR2 Q92731 3/20 0.40
▸ MEN1 O00255 3/20 0.39
▸ MAPT P10636 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ PKM P14618 2/20 0.39
▸ ESR1 P03372 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ ALDH1A1 P00352 3/20 0.34
▸ MCOLN3 Q8TDD5 1/20 0.34
▸ KDM4E B2RXH2 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18912541 0.98 ESR2 (0.41) ESR2MEN1MAPTKMT2APKM
SCHEMBL12878725 0.95 ESR2 (0.37) ESR2MEN1MAPTKMT2APKM
SCHEMBL4407792 0.91 MAPT (0.38) ESR2MEN1MAPTKMT2APKM
SCHEMBL13892234 0.87 MAPT (0.41) MEN1MAPTKMT2APKMSMN1; SMN2
SCHEMBL12545055 0.86 ESR2 (0.37) ESR2MEN1MAPTKMT2AESR1
SCHEMBL17849097 0.86 ESR2 (0.37) ESR2MEN1MAPTKMT2AESR1
SCHEMBL15188533 0.86 MAPT (0.36) ESR2MEN1MAPTKMT2APKM
SCHEMBL12587556 0.84 ESR2 (0.38) ESR2MEN1MAPTKMT2AESR1
SCHEMBL13780495 0.83 MAPT (0.47) MEN1MAPTKMT2APKMSMN1; SMN2
SCHEMBL17642065 0.82 S1PR4 (0.42) ESR2MEN1MAPTKMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080099-B2 Fluorine-bridged associations for optoelectronic applications MERCK PATENT GMBH (DE) 2015-07-14 — — US disclosed
US-9080099-B2 Fluorine-bridged associations for optoelectronic applications MERCK PATENT GMBH (DE) 2015-07-14 — — US disclosed
US-8637853-B2 Optoelectronic device MERCK PATENT GMBH (DE) 2014-01-28 — — US disclosed
US-8637853-B2 Optoelectronic device MERCK PATENT GMBH (DE) 2014-01-28 — — US disclosed
EP-2318473-B1 FLUORINE-BRIDGED ASSOCIATIONS FOR OPTOELECTRONIC APPLICATIONS MERCK PATENT GMBH (DE) 2013-05-29 — — EP disclosed
US-8445630-B2 Polymers BASF SE (DE) 2013-05-21 — — US disclosed
EP-2046785-B1 1,4-BIS(2-THIENYLVINYL)BENZOL DERIVATIVES AND THEIR USE MERCK PATENT GMBH (DE) 2013-02-27 — — EP disclosed
US-8236968-B2 1,4-bis(2-thienylvinyl)benzol derivatives and their use MERCK PATENT GMBH (DE) 2012-08-07 — — US disclosed
US-8236968-B2 1,4-bis(2-thienylvinyl)benzol derivatives and their use MERCK PATENT GMBH (DE) 2012-08-07 — — US disclosed
US-8221906-B2 Electroluminescent polymers for electronic applications BASF SE (DE) 2012-07-17 — — US disclosed
US-20090309068-A1 NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS UDC IRELAND LIMITED (IE) 2009-12-17 — — US disclosed
US-20090105447-A1 Novel Polymers UDC IRELAND LIMITED (IE) 2009-04-23 — — US disclosed
US-20090005505-A1 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2009-01-01 — — US disclosed
US-20090005505-A1 polymeric light emitting diodes; longer operating lifetime; brightness with lower energy; MERCK PATENT GMBH (DE) 2009-01-01 — — US disclosed
US-7323533-B2 Conjugated polymers containing spirobifluorene units and the use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2008-01-29 — — US disclosed
US-20070265473-A1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2007-11-15 — — US disclosed
US-7288617-B2 Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof MERCK PATENT GMBH (DE) 2007-10-30 — — US disclosed
WO-2007068325-A1 TRIARYLAMINE-ARYLVINYLENE MOIETY-CONTAINING CONJUGATED POLYMERS, THEIR PRODUCTION AND USE MERCK PATENT GMBH (DE) 2007-06-21 — — WO disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 — — US disclosed
US-20070060736-A1 Conjugated polymers containing dihydrophenanthrene units and use thereof MERCK PATENT GMBH (DE) 2007-03-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105447-A1 Novel Polymers PLEC, VIM, PUF60 ESR2 3142/4885MEN1 3994/4885MAPT 123/4885
US-20070265473-A1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF ALDH1A2, SELE, PPOX ESR2 1426/4885MEN1 3100/4885MAPT 1185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.