Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | PKLR | P30613 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187975 | 0.85 | ATM (0.58) | PKMPKLRATMPPARGSMN1; SMN2 | |
| SCHEMBL17849560 | 0.81 | GAA (0.59) | PKMALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL16210882 | 0.80 | MEN1 (0.59) | PKMPKLRATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL20021987 | 0.79 | PGR (0.77) | PKMPKLRATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL29549847 | 0.79 | PGR (0.77) | PKMPKLRATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL28396503 | 0.79 | PGR (0.77) | PKMPKLRATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL8278382 | 0.79 | SMN1; SMN2 (0.67) | PKMPKLRATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL13689995 | 0.78 | SMN1; SMN2 (0.58) | PKMPKLRATMPPARGSMN1; SMN2 | |
| SCHEMBL27790749 | 0.78 | ATM (0.73) | PKMPKLRATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL9175506 | 0.77 | SMN1; SMN2 (0.76) | PKMPKLRATMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |