Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.67 |
| ▸ | PKLR | P30613 | 1/20 | 0.67 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | IL1RN | P18510 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | PLAU | P00749 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021987 | 1.00 | PGR (0.77) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL29549847 | 1.00 | PGR (0.77) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9479593 | 0.93 | PGR (0.73) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL4556438 | 0.86 | KMT2A (0.60) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9465080 | 0.86 | KMT2A (0.70) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9942088 | 0.86 | ATM (0.72) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL20021984 | 0.86 | ATM (0.72) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL808105 | 0.86 | ATM (0.72) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9942091 | 0.86 | ATM (0.68) | PGRATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL10978762 | 0.86 | KMT2A (0.60) | PGRATMSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170905-B | Synthetic method of sulfonamide compound | 台州学院 | 2022-04-29 | — | — | CN | disclosed |
| CN-111170905-A | Synthetic method of sulfonamide compound | 台州学院 | 2020-05-19 | — | — | CN | disclosed |