SCHEMBL17849669

SCHEMBL17849669

CC1(C)c2cc(-c3ccc(N(c4ccccc4)c4cc5ccc6cccc7ccc(c4)c5c67)cc3)cc3ccc4cc(-c5cccnc5)cc1c4c23

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 9/20 0.43
CYP11B1 P15538 9/20 0.43
CYP19A1 P11511 6/20 0.43
CYP17A1 P05093 4/20 0.43
CYP2A6 P11509 1/20 0.38
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
DHODH Q02127 1/20 0.34
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PGR P06401 1/20 0.34
GRM2 Q14416 1/20 0.34
ABL1 P00519 1/20 0.33
BCR P11274 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909623 0.95 CYP11B2 (0.44) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL17849678 0.94 CYP11B2 (0.46) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL17849665 0.94 CYP11B2 (0.46) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL17849664 0.92 CYP11B2 (0.51) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL15909626 0.89 CYP19A1 (0.36) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL15909655 0.89 CYP19A1 (0.43) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL15909650 0.88 CYP11B2 (0.41) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL15909737 0.88 CYP11B1 (0.51) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6
SCHEMBL15909624 0.87 CYP11B2 (0.40) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL15909758 0.87 CYP11B2 (0.53) CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed