SCHEMBL15909626

SCHEMBL15909626

CC1(C)c2cccc3ccc4cc(-c5ccc(-c6ccc(N(c7ccccc7)c7cccnc7)cc6)cc5)cc1c4c23

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.36
CYP11B1 P15538 3/20 0.36
CYP11B2 P19099 3/20 0.36
CYP17A1 P05093 2/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.34
PDK2 Q15119 2/20 0.32
SIRT2 Q8IXJ6 1/20 0.32
CYP2A6 P11509 1/20 0.32
CCR5 P51681 1/20 0.32
HDAC6 Q9UBN7 2/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
GRM1 Q13255 1/20 0.31
KCNN4 O15554 1/20 0.31
KCNA5 P22460 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909624 0.95 CYP11B2 (0.40) CYP19A1CYP11B1CYP11B2CYP17A1PTGDR2
SCHEMBL15909623 0.95 CYP11B2 (0.44) CYP19A1CYP11B1CYP11B2CYP17A1PDK2
SCHEMBL15909655 0.93 CYP19A1 (0.43) CYP19A1CYP11B1CYP11B2CYP17A1PTGDR2
SCHEMBL15909644 0.92 PDK2 (0.37) CYP19A1CYP11B1CYP11B2CYP17A1PTGDR2
SCHEMBL13888806 0.90 LPL (0.34) KDM4ELPLLIPGCYP3A4
SCHEMBL13888804 0.90 LPL (0.34) KDM4ELPLLIPGCYP3A4
SCHEMBL17849608 0.90 LPL (0.34) KDM4ELPLLIPGCYP3A4
SCHEMBL13888803 0.90 LPL (0.34) KDM4ELPLLIPGCYP3A4
SCHEMBL17849669 0.89 CYP11B2 (0.43) CYP19A1CYP11B1CYP11B2CYP17A1PDK2
SCHEMBL17849678 0.89 CYP11B2 (0.46) CYP19A1CYP11B1CYP11B2CYP17A1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed