Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194844 | 0.89 | GAA (0.56) | GAAHPGDALDH1A1POLBMAPT | |
| SCHEMBL7401006 | 0.86 | NAMPT (0.64) | NAMPTGAAHPGDNPC1AKR1C3 | |
| SCHEMBL10194840 | 0.85 | GAA (0.50) | NAMPTGAAHPGDALDH1A1POLB | |
| SCHEMBL15317709 | 0.85 | NAMPT (0.55) | NAMPTGAAHPGDNPC1ALDH1A1 | |
| SCHEMBL10194843 | 0.84 | SPHK2 (0.55) | GAAHPGDNPC1ALDH1A1POLB | |
| SCHEMBL12237829 | 0.81 | HRH3 (0.61) | GAAHPGD | |
| SCHEMBL2743749 | 0.81 | HRH3 (0.61) | GAAHPGD | |
| SCHEMBL12948012 | 0.81 | ALDH1A1 (0.49) | NAMPTGAAHPGDALDH1A1POLB | |
| SCHEMBL2743746 | 0.81 | HRH3 (0.61) | GAAHPGD | |
| SCHEMBL13431503 | 0.80 | NAMPT (0.51) | NAMPTGAAHPGDNPC1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655357-B1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO SA (CH) | 2016-06-22 | — | — | EP | disclosed |