Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 6/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729189 | 0.84 | BRPF1 (0.56) | TRIM24TRIM33BRPF1NR4A2HTR2A | |
| SCHEMBL26980813 | 0.81 | DYRK1A (0.49) | NR4A2HTR2AARAHRHTR6 | |
| SCHEMBL20355028 | 0.79 | DYRK1A (0.47) | ARNR3C1PGRNR3C2HTR6 | |
| SCHEMBL31319577 | 0.78 | CSNK2A2 (0.34) | BRPF1 | |
| SCHEMBL20354813 | 0.76 | CSNK2A2 (0.46) | MAPTSMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL30286837 | 0.76 | CSNK2A2 (0.46) | MAPTSMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL31438275 | 0.75 | REN (0.34) | TRIM24TRIM33NPSR1MAPTAR | |
| SCHEMBL27036397 | 0.75 | CSNK2A2 (0.50) | MAPTNR3C1CNR2 | |
| SCHEMBL6587236 | 0.74 | PARP1 (0.51) | NPSR1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1077391 | 0.74 | CCR8 (0.35) | TRIM24TRIM33BRPF1ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643299-B1 | BIPYRIDINE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OR CONDITIONS | NOSCIRA SA (ES) | 2016-06-22 | — | — | EP | disclosed |