SCHEMBL17850563

SCHEMBL17850563

COC(=O)N1CCCC1C(=O)N1CCCC1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5219163 0.82 HSD17B10 (0.77) HSD17B10
SCHEMBL3280014 0.82 HSD17B10 (0.77) HSD17B10
SCHEMBL18461898 0.82 HSD17B10 (0.77) HSD17B10
SCHEMBL6979623 0.81 HSD17B10 (0.75) HSD17B10
SCHEMBL3274878 0.81 HSD17B10 (0.75) HSD17B10
SCHEMBL31257712 0.80 RAB9A (0.61) HSD17B10
SCHEMBL9169937 0.80 RAB9A (0.61) HSD17B10
SCHEMBL27431488 0.80
SCHEMBL13864545 0.80 RAB9A (0.45) HSD17B10
SCHEMBL9169924 0.80 RAB9A (0.61) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714036-B1 SUBSITUTED ALIPHANES, CYCLOPHANES, HETERAPHANES, HETEROPHANES, HETERO-HETERAPHANES AND METALLOCENES USEFUL FOR TREATING HCV INFECTIONS ACHILLION PHARMACEUTICALS INC (US) 2016-06-22 EP disclosed