Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431733 | 0.84 | KDM1A (0.42) | KDM1AALDH1A1GPR84FAAHTRPV1 | |
| SCHEMBL431732 | 0.84 | KDM1A (0.42) | KDM1AALDH1A1GPR84FAAHTRPV1 | |
| SCHEMBL11575290 | 0.81 | — | — | |
| SCHEMBL12377078 | 0.81 | — | — | |
| SCHEMBL22473042 | 0.77 | KDM1A (0.48) | KDM1AALDH1A1GPR84FAAHTRPV1 | |
| SCHEMBL15383250 | 0.73 | KDM1A (0.56) | KDM1AALDH1A1FAAHTRPV1 | |
| SCHEMBL9036334 | 0.73 | KDM1A (0.56) | KDM1AALDH1A1FAAHTRPV1 | |
| SCHEMBL8175490 | 0.72 | — | — | |
| SCHEMBL24131906 | 0.71 | KDM1A (0.58) | KDM1AALDH1A1FAAHTRPV1 | |
| SCHEMBL37295 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714036-B1 | SUBSITUTED ALIPHANES, CYCLOPHANES, HETERAPHANES, HETEROPHANES, HETERO-HETERAPHANES AND METALLOCENES USEFUL FOR TREATING HCV INFECTIONS | ACHILLION PHARMACEUTICALS INC (US) | 2016-06-22 | — | — | EP | disclosed |