SCHEMBL431732

SCHEMBL431732

CCC/C=C/CNC/C=C/CCC

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.42
ALDH1A1 P00352 1/20 0.40
GPR84 Q9NQS5 1/20 0.37
FAAH O00519 2/20 0.35
TRPV1 Q8NER1 2/20 0.35
TSHR P16473 2/20 0.33
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL431733 1.00 KDM1A (0.42) KDM1AALDH1A1GPR84FAAHTRPV1
SCHEMBL22473042 0.86 KDM1A (0.48) KDM1AALDH1A1GPR84FAAHTRPV1
SCHEMBL17850574 0.84 KDM1A (0.36) KDM1AALDH1A1GPR84FAAHTRPV1
SCHEMBL9206591 0.82 FAAH (0.48) KDM1AALDH1A1FAAHTRPV1TSHR
SCHEMBL9036334 0.82 KDM1A (0.56) KDM1AALDH1A1FAAHTRPV1TSHR
SCHEMBL15383250 0.82 KDM1A (0.56) KDM1AALDH1A1FAAHTRPV1TSHR
SCHEMBL24131906 0.80 KDM1A (0.58) KDM1AALDH1A1FAAHTRPV1TSHR
SCHEMBL37295 0.79
SCHEMBL37294 0.79
SCHEMBL56167 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334412-B2 Process for preparing 3-(methylthio)propanal SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-18 US disclosed
US-20120022295-A1 PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-26 US disclosed
EP-0804525-A4 DIMERCAPTOTHIADIAZOLE-MERCAPTAN COUPLED COMPOUNDS AS MULTIFUNCTIONAL ADDITIVES FOR LUBRICANTS AND FUELS MOBIL OIL CORP (US) 1998-09-02 EP disclosed
EP-0804525-A1 DIMERCAPTOTHIADIAZOLE-MERCAPTAN COUPLED COMPOUNDS AS MULTIFUNCTIONAL ADDITIVES FOR LUBRICANTS AND FUELS MOBIL OIL CORPORATION (US) 1997-11-05 EP disclosed
US-5538652-A OXIDATION, CORROSION AND WEAR RESISTANT EXTREME PRESSURE OIL ADDITIVES FOR ENGINE LUBRICANTS MOBIL OIL CORPORATION (US) 1996-07-23 US disclosed
WO-1996006903-A1 DIMERCAPTOTHIADIAZOLE-MERCAPTAN COUPLED COMPOUNDS AS MULTIFUNCTIONAL ADDITIVES FOR LUBRICANTS AND FUELS MOBIL OIL CORPORATION (US) 1996-03-07 WO disclosed
US-RE32316-E HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1986-12-30 US disclosed
US-4256903-A REACTING SULFUR DIOXIDE AND CONJUGATED DIENES IN THE PRESENCE OF A MONO OR DI-ALKENYL AMINE PHILLIPS PETROLEUM COMPANY (US) 1981-03-17 US disclosed
US-3983168-A HERBICIDES MOBIL OIL CORPORATION (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120022295-A1 PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL PTMA, TMT1A, MGMT KDM1A 4231/4885ALDH1A1 32/4885GPR84 3947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.