SCHEMBL17850696

SCHEMBL17850696

Cc1ccc2oc3ccc(-n4c5ccccc5c5cc(-n6c7ccccc7n7c8ccccc8nc67)ccc54)cc3c2c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
NR1I2 O75469 1/20 0.34
AHR P35869 1/20 0.34
POLB P06746 4/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
LCK P06239 2/20 0.33
SRC P12931 2/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21412960 0.96 HPGD (0.34) KMT2AMEN1NR1I2AHRPOLB
SCHEMBL16920090 0.96 KMT2A (0.34) KMT2AMEN1NR1I2AHRPOLB
SCHEMBL16920057 0.96 KMT2A (0.34) KMT2AMEN1NR1I2AHRPOLB
SCHEMBL12800986 0.94 GABRP (0.37) KMT2AMEN1NR1I2AHRPOLB
SCHEMBL19726257 0.93 GABRP (0.36) KMT2AMEN1POLBMAPTKDM4E
SCHEMBL19275393 0.92 PDE10A (0.36) KMT2AMEN1NR1I2AHRPOLB
SCHEMBL16920055 0.91 ALDH1A1 (0.35) KMT2APOLBKDM4ELMNAHPGD
SCHEMBL16920065 0.90 HPGD (0.33) KMT2AMEN1NR1I2AHRPOLB
SCHEMBL17850698 0.90 POLB (0.32) KMT2AMEN1NR1I2AHRPOLB
SCHEMBL16920073 0.89 PDE10A (0.35) KMT2AMEN1NR1I2AHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2017-12-21 US disclosed
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2017-12-21 US disclosed
WO-2016097983-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 WO disclosed
EP-3034507-A1 1-functionalized dibenzofurans and dibenzothiophenes for organic light emitting diodes (OLEDs) Idemitsu Kosan Co., Ltd (JP) 2016-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) OCIAD1, OCIAD2, DDT KMT2A 4080/4885MEN1 3404/4885NR1I2 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.