SCHEMBL17850756

SCHEMBL17850756

Cc1cccc2c1oc1ccc(-n3c4ccccc4n4c5cc(-n6c7ccccc7c7ccccc76)ccc5nc34)cc12

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
PPARG P37231 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NR2E3 Q9Y5X4 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
TP53 P04637 1/20 0.30
LCK P06239 1/20 0.30
LYN P07948 1/20 0.30
KIT P10721 1/20 0.30
SRC P12931 1/20 0.30
BRAF P15056 1/20 0.30
TYK2 P29597 1/20 0.30
KDR P35968 1/20 0.30
ZAP70 P43403 1/20 0.30
SYK P43405 1/20 0.30
JAK3 P52333 1/20 0.30
MAPK10 P53779 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19726260 0.93 LCK (0.33) ALDH1A1LMNAPPARGNPSR1RXFP1
SCHEMBL16920054 0.92 LCK (0.35) ALDH1A1LMNAPPARGNPSR1RXFP1
SCHEMBL19726257 0.87 GABRP (0.36) ALDH1A1LMNATP53LCKSRC
SCHEMBL19726258 0.86 TSHR (0.32) ALDH1A1LMNAPPARGNPSR1RXFP1
SCHEMBL17850697 0.86 TSHR (0.32) LCKLYNKITSRCBRAF
SCHEMBL16920056 0.84 ALDH1A1 (0.40) ALDH1A1LMNAPPARGNPSR1RXFP1
SCHEMBL12800968 0.82 KDM4E (0.30)
SCHEMBL12800971 0.82
SCHEMBL19726256 0.81 RXFP1 (0.39) ALDH1A1LMNAPPARGNPSR1RXFP1
SCHEMBL17850695 0.81 TSHR (0.33) LMNATP53LCKLYNKIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2017-12-21 US disclosed
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2017-12-21 US disclosed
WO-2016097983-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 WO disclosed
EP-3034507-A1 1-functionalized dibenzofurans and dibenzothiophenes for organic light emitting diodes (OLEDs) Idemitsu Kosan Co., Ltd (JP) 2016-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362241-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) OCIAD1, OCIAD2, DDT ALDH1A1 99/4885LMNA 4719/4885PPARG 2527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.