Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15641223 | 0.85 | MAOB (0.40) | MAOBTSHRSMN1; SMN2CMA1LMNA | |
| SCHEMBL5350084 | 0.83 | MAOB (0.40) | MAOBTSHRSMN1; SMN2CMA1LMNA | |
| SCHEMBL1786086 | 0.83 | TRPA1 (0.40) | ALDH1A1DDB1CRBN | |
| SCHEMBL15641200 | 0.82 | MAOB (0.39) | MAOBTSHRSMN1; SMN2CMA1FFAR1 | |
| SCHEMBL15643474 | 0.82 | MAOB (0.39) | MAOBTSHRSMN1; SMN2CMA1LMNA | |
| SCHEMBL15641142 | 0.82 | MAOB (0.40) | MAOBTSHRSMN1; SMN2CMA1LMNA | |
| SCHEMBL16473223 | 0.81 | MAOB (0.39) | MAOBTSHRSMN1; SMN2CMA1CNR1 | |
| SCHEMBL17135347 | 0.81 | TSHR (0.41) | MAOBTSHRSMN1; SMN2CMA1LMNA | |
| SCHEMBL1822117 | 0.81 | GLA (0.43) | SMN1; SMN2CMA1ALDH1A1HSD11B1 | |
| SCHEMBL15641431 | 0.81 | MAOB (0.39) | MAOBTSHRSMN1; SMN2CMA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124877-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | KUREHA CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-2315752-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | Kureha Corporation (JP) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010023862-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | KUREHA CORPORATION (JP) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124877-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | CYP8B1, CBR3, CBR1 | MAOB 3910/4885TSHR 3518/4885SMN1; SMN2 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.