Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785146 | 0.83 | MAOB (0.42) | CRBNDDB1ALDH1A1 | |
| SCHEMBL15641434 | 0.82 | TRPA1 (0.35) | TRPA1GAAROCK2 | |
| SCHEMBL9264434 | 0.71 | TRPA1 (0.40) | TRPA1GAAALDH1A1 | |
| SCHEMBL1822117 | 0.71 | GLA (0.43) | GAAALDH1A1 | |
| SCHEMBL9166295 | 0.70 | PTGS2 (0.56) | — | |
| SCHEMBL5517558 | 0.70 | PTGS2 (0.52) | ALDH1A1 | |
| SCHEMBL15641223 | 0.69 | MAOB (0.40) | CRBNALDH1A1 | |
| SCHEMBL11270285 | 0.69 | GLA (0.60) | GAACRBNDDB1ALDH1A1 | |
| SCHEMBL11794283 | 0.69 | PTGS2 (0.51) | ALDH1A1 | |
| SCHEMBL3051430 | 0.69 | ALDH1A1 (0.44) | GAAROCK2CRBNDDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124877-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | KUREHA CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-2315752-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | Kureha Corporation (JP) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010023862-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | KUREHA CORPORATION (JP) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124877-A1 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF | CYP8B1, CBR3, CBR1 | TRPA1 506/4885GAA 4632/4885ROCK2 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.