SCHEMBL17852129

SCHEMBL17852129

CC(C)(O)c1ccc(Br)cc1-c1ccc2ccccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.47
ESR2 Q92731 3/20 0.42
ESR1 P03372 2/20 0.42
GSTP1 P09211 1/20 0.42
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
DHODH Q02127 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
ALOX5 P09917 1/20 0.38
SLC22A12 Q96S37 1/20 0.37
MIF P14174 1/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
PTGER3 P43115 2/20 0.36
CYP11B1 P15538 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14063309 0.82 HDAC4 (0.49) ESR2ESR1GSTP1HDAC4HDAC2
SCHEMBL16585739 0.82 PTGDR2 (0.43) ESR2AKR1C3AKR1C2ALOX5
SCHEMBL13828954 0.80 ADORA3 (0.40) CYP2A6SLC6A3MIFTRPV1
SCHEMBL19082479 0.78 CYP1A1 (0.38) ALOX5CYP1A2
SCHEMBL19082503 0.77 KCNJ11 (0.31)
SCHEMBL25905211 0.77 MAOB (0.40) CYP2A6
SCHEMBL17836992 0.76 KCNJ11 (0.38) CYP2A6ESR2ESR1HDAC8AKR1C3
SCHEMBL18311777 0.76 CYP2A6 (0.43) CYP2A6DHODHCYP11B1CYP11B2
SCHEMBL17852133 0.76 MEN1 (0.40) CYP2A6CYP11B1
SCHEMBL13152938 0.76 TRPV1 (0.47) ESR2GSTP1HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160181542-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed
US-20160181542-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160181542-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME L1CAM, H1-10, H1-0 CYP2A6 2276/4885ESR2 82/4885ESR1 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.