SCHEMBL19082479

SCHEMBL19082479

CC(C)(O)c1ccc(Br)cc1-c1ccc2c(c1)oc1c3ccccc3ccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 8/20 0.38
CYP1B1 Q16678 8/20 0.38
CYP1A2 P05177 7/20 0.38
CSNK2A2 P19784 2/20 0.38
CSNK2B P67870 2/20 0.38
CSNK2A1 P68400 2/20 0.38
PSMD14 O00487 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
DYRK1A Q13627 1/20 0.37
ALOX5 P09917 1/20 0.35
KMT2A Q03164 1/20 0.34
MCL1 Q07820 1/20 0.34
ABCB1 P08183 3/20 0.34
ABCG2 Q9UNQ0 3/20 0.34
ABCC1 P33527 2/20 0.34
PRKDC P78527 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PDE5A O76074 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19077633 0.78 ALOX5 (0.40) DYRK1AALOX5KMT2APRKDCCYP2C19
SCHEMBL18271472 0.78 MAOB (0.44) CYP1A1CYP1B1CYP1A2CSNK2A2CSNK2B
SCHEMBL17852129 0.78 CYP2A6 (0.47) CYP1A2ALOX5
SCHEMBL29595884 0.78 KMT2A (0.45) CYP1A1CYP1B1CYP1A2DYRK1AKMT2A
SCHEMBL16067566 0.78 KMT2A (0.45) CYP1A1CYP1B1CYP1A2DYRK1AKMT2A
SCHEMBL30808543 0.78 KMT2A (0.45) CYP1A1CYP1B1CYP1A2DYRK1AKMT2A
SCHEMBL26469935 0.76 NMUR2 (0.41) ALOX5KMT2AKDM4EALDH1A1TP53
SCHEMBL16067564 0.76 MAOB (0.47) CYP1A1CYP1B1CYP1A2CSNK2A2CSNK2B
SCHEMBL19082480 0.75 ALDH1A1 (0.47) CYP1A2TDP1ALOX5KMT2AKDM4E
SCHEMBL19082503 0.75 KCNJ11 (0.31) MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 CYP1A1 184/4885CYP1B1 260/4885CYP1A2 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.