SCHEMBL1785225

SCHEMBL1785225

CC(CC(C)OC(=O)c1ccccc1Br)OC(=O)c1ccccc1Br

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
HTT P42858 1/20 0.59
ALDH1A1 P00352 4/20 0.46
SCN1A P35498 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN3A Q9NY46 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
HPGD P15428 2/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
USP2 O75604 1/20 0.42
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31454731 1.00 TSHR (0.59) TSHRHTTALDH1A1SCN1ASCN2A
SCHEMBL4577700 0.92 TSHR (0.55) TSHRHTTALDH1A1SCN1ASCN2A
SCHEMBL1783465 0.85 ALDH1A1 (0.60) TSHRHTTALDH1A1SCN1ASCN2A
SCHEMBL30784110 0.84 NPC1 (0.54) TSHRHTTALDH1A1NPC1RAB9A
SCHEMBL1785248 0.84 TSHR (0.52) TSHRHTTALDH1A1NPC1RAB9A
SCHEMBL1928503 0.84 NPC1 (0.54) TSHRHTTALDH1A1NPC1RAB9A
SCHEMBL29395041 0.82 TSHR (0.58) TSHRHTTALDH1A1SCN1ASCN2A
SCHEMBL7741930 0.82 TSHR (0.58) TSHRHTTALDH1A1SCN1ASCN2A
SCHEMBL14690195 0.81 SMN1; SMN2 (0.59) TSHRALDH1A1SCN1ASCN2ASCN3A
SCHEMBL2408720 0.81 SMN1; SMN2 (0.59) TSHRALDH1A1SCN1ASCN2ASCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3059263-B1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
US-9951157-B2 Spherical carriers for olefin polymerization catalyst, catalyst components, catalyst, and preparation methods therefor CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2018-04-24 US claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
US-20160251457-A1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-09-01 US claimed
EP-3059263-A1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR China Petroleum&Chemical Corporation (CN) 2016-08-24 EP claimed
US-9068026-B2 Magnesium halide adducts, catalyst components and catalysts comprising the same, and preparation processes thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-06-30 US claimed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US claimed
US-20250066513-A1 Catalyst System For Enhanced Stereo-Specificity Of Olefin Polymerization FORMOSA PLASTICS CORP USA (US) 2025-02-27 US disclosed
US-20250026868-A1 OLEFIN POLYMERIZATION ZIEGLER-NATTA CATALYST COMPONENTS ANDPROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS THEREWITH FORMOSA PLASTICS CORPORATION, USA (US) 2025-01-23 US disclosed
US-20230091516-A1 Olefin polymerization Ziegler-Natta catalyst components and process for the production of olefin polymers therewith FORMOSA PLASTICS CORP USA (US) 2023-03-23 US disclosed
US-20230092187-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT HAVING CARBONATE COMPOUNDS FORMOSAPLASTICSCORPORATION USA (US) 2023-03-23 US disclosed
EP-3059263-B1 SPHERICAL CARRIERS FOR OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENTS, CATALYST, AND PREPARATION METHODS THEREFOR CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP disclosed
US-10954324-B2 Catalyst component for high activity and high stereoselectivity in olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2021-03-23 US disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 TSHR 921/4885HTT 4767/4885ALDH1A1 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.