Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690195 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL13328208 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL15110945 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL2838593 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL17797889 | 0.85 | ALDH1A1 (0.62) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL14125173 | 0.84 | MAPT (0.48) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL8995973 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL7741930 | 0.83 | TSHR (0.58) | SMN1; SMN2KDM4EALDH1A1TSHRSCN1A | |
| SCHEMBL1786549 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL277670 | 0.83 | NPC1 (0.56) | SMN1; SMN2KDM4EADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053935-B1 | CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2019-05-08 | — | — | EP | claimed |
| US-9822196-B2 | Catalyst composition for olefin polymerization and application of same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2017-11-21 | — | — | US | claimed |
| US-20160244538-A1 | CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2016-08-25 | — | — | US | claimed |
| EP-3053935-A1 | CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME | China Petroleum & Chemical Corporation (CN) | 2016-08-10 | — | — | EP | claimed |
| EP-3053935-B1 | CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2019-05-08 | — | — | EP | disclosed |
| CN-109553705-A | A kind of catalytic component and preparation method thereof for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109553711-A | A kind of catalytic component and its catalyst for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109553708-A | A kind of catalytic component and preparation method thereof for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109553709-A | A kind of catalytic component and its catalyst for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109553703-A | A kind of catalytic component and preparation method thereof for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109553712-A | A kind of catalytic component and its catalyst for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| EP-2539378-B1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | GRACE W R & CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2539379-A1 | AMIDE ESTER INTERNAL ELECTRON AND PROCESS | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| EP-2539378-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120322962-A1 | Procatalyst Composition with Substituted Amide Ester Internal Electron Donor | W. R. GRACE & CO.-CONN. | 2012-12-20 | — | — | US | disclosed |
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120316299-A1 | Amide Ester Internal Electron Donor and Process | W. R. GRACE & CO.-CONN. | 2012-12-13 | — | — | US | disclosed |
| WO-2011106500-A1 | AMIDE ESTER INTERNAL ELECTRON AND PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106494-A1 | PROCATALYST COMPOSITION WITH SUBSTITUTED AMIDE ESTER INTERNAL ELECTRON DONOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | NAT10, NAT1, NAA50 | SMN1; SMN2 3716/4885KDM4E 4046/4885ADRB2 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.