SCHEMBL1785227

SCHEMBL1785227

CC(O)CC(C)O.O=C(O)c1ccccc1Br.O=C(O)c1ccccc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
PRNP P04156 1/20 0.44
MAPT P10636 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
F2R P25116 2/20 0.40
NPC1 O15118 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4577704 1.00 ALDH1A1 (0.46) ALDH1A1HPGDALOX15PRNPMAPT
Propylene Glycol SCHEMBL5085714 0.89 ALDH1A1 (0.46) ALDH1A1HPGDALOX15PRNPMAPT
SCHEMBL5081262 0.87 ALDH1A1 (0.50) ALDH1A1HPGDALOX15PRNPMAPT
Methyl Alcohol SCHEMBL38658039 0.82 ALDH1A1 (0.59) ALDH1A1HPGDALOX15PRNPMAPT
SCHEMBL49806 0.82 ALDH1A1 (0.65) ALDH1A1HPGDALOX15PRNPMAPT
SCHEMBL5082140 0.81 ALDH1A1 (0.45) ALDH1A1HPGDALOX15PRNPMAPT
SCHEMBL17799574 0.80 ALDH1A1 (0.62) ALDH1A1HPGDALOX15PRNPMAPT
SCHEMBL8613579 0.80 ALDH1A1 (0.62) ALDH1A1HPGDALOX15PRNPMAPT
SCHEMBL2112435 0.80 ALDH1A1 (0.62) ALDH1A1HPGDALOX15PRNPMAPT
Hydrochloric Acid SCHEMBL1586914 0.80 ALDH1A1 (0.62) ALDH1A1HPGDALOX15PRNPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9068026-B2 Magnesium halide adducts, catalyst components and catalysts comprising the same, and preparation processes thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-06-30 US claimed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US claimed
US-20250066513-A1 Catalyst System For Enhanced Stereo-Specificity Of Olefin Polymerization FORMOSA PLASTICS CORP USA (US) 2025-02-27 US disclosed
US-20250026868-A1 OLEFIN POLYMERIZATION ZIEGLER-NATTA CATALYST COMPONENTS ANDPROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS THEREWITH FORMOSA PLASTICS CORPORATION, USA (US) 2025-01-23 US disclosed
US-20230092187-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT HAVING CARBONATE COMPOUNDS FORMOSAPLASTICSCORPORATION USA (US) 2023-03-23 US disclosed
US-20230091516-A1 Olefin polymerization Ziegler-Natta catalyst components and process for the production of olefin polymers therewith FORMOSA PLASTICS CORP USA (US) 2023-03-23 US disclosed
US-10954324-B2 Catalyst component for high activity and high stereoselectivity in olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2021-03-23 US disclosed
US-20200354485-A1 Olefin polymerization Ziegler-Natta catalyst components and process for the production of olefin polymers therewith FORMOSA PLASTICS CORP USA (US) 2020-11-12 US disclosed
US-20200316575-A1 Olefin Polymerization Catalyst Component Having Carbonate Compounds FORMOSA PLASTICS CORP USA (US) 2020-10-08 US disclosed
EP-3486263-A2 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE W.R. Grace & CO. - CONN. (US) 2019-05-22 EP disclosed
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-03-26 US disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
EP-1478617-A4 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2006-04-19 EP disclosed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 ALDH1A1 3489/4885HPGD 3203/4885ALOX15 260/4885
US-10239969-B2 Spherical magnesium halide adduct, a catalyst component and a catalyst for olefin polymerization prepared therefrom MSMO1, SCO2, RTF1 ALDH1A1 3333/4885HPGD 831/4885ALOX15 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.