SCHEMBL17852971

SCHEMBL17852971

C=Cc1ccc(C23CC4CC(C2)CC(c2ccc(N(c5ccc(C)cc5)c5ccc(C)cc5)cc2)(C4)C3)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.48
MEN1 O00255 5/20 0.48
PGR P06401 4/20 0.41
HSD11B1 P28845 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17852977 0.92 HSD11B1 (0.42) KMT2AMEN1PGRHSD11B1POLB
SCHEMBL17852974 0.91 KMT2A (0.41) KMT2AMEN1PGRHSD11B1SMN1; SMN2
SCHEMBL17852864 0.89 PGR (0.41) KMT2AMEN1PGRHSD11B1POLB
SCHEMBL17852895 0.89 PGR (0.41) KMT2AMEN1PGRHSD11B1POLB
SCHEMBL17852922 0.89 PGR (0.41) KMT2AMEN1PGRHSD11B1POLB
SCHEMBL13049518 0.89 KMT2A (0.57) KMT2AMEN1PGRHSD11B1SMN1; SMN2
SCHEMBL17852969 0.88 GRIN2D (0.49) KMT2AMEN1PGRHSD11B1SMN1; SMN2
SCHEMBL17852911 0.86 PGR (0.39) KMT2AMEN1PGRHSD11B1SMN1; SMN2
SCHEMBL17855983 0.86 HSD11B1 (0.44) KMT2AMEN1PGRHSD11B1SMN1; SMN2
SCHEMBL17852954 0.85 KMT2A (0.38) KMT2AMEN1PGRHSD11B1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308735-B2 Material for organic light-emitting device and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-06-04 US disclosed
US-20160181535-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-23 US disclosed
US-20160181535-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-23 US disclosed